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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC24A5 All Species: 24.55
Human Site: S294 Identified Species: 41.54
UniProt: Q71RS6 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q71RS6 NP_995322.1 500 54888 S294 Q V S E D P P S V F N M P E A
Chimpanzee Pan troglodytes XP_510380 500 54850 S294 Q V S E D P P S V F N I P E A
Rhesus Macaque Macaca mulatta XP_001112601 500 55038 S294 Q V S E D P P S V F N M P E A
Dog Lupus familis XP_851849 501 55168 S295 Q V S E D P P S V F N M P E A
Cat Felis silvestris
Mouse Mus musculus Q8C261 501 54965 S295 Q V S E D P P S V F S M P E A
Rat Rattus norvegicus Q9EPQ0 624 69371 Q337 R M L I N E R Q R L I N S R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517974 336 36438 I150 L W V L S L P I I T L L F L T
Chicken Gallus gallus Q9IAL7 651 72677 S365 P L A E E L G S Y G N L K Y Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q49SH1 513 56764 S307 E I S D E H K S V F S M P D H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VN12 642 70657 N418 Q A T S A G G N D Y Y K S T D
Honey Bee Apis mellifera XP_624828 470 51842 P286 L I F M C T I P D C E K P R F
Nematode Worm Caenorhab. elegans P34315 590 66151 V342 E M N I F Q K V I A V L N T I
Sea Urchin Strong. purpuratus XP_780438 570 63240 S348 G N V P R S D S I C K D E S V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LJI2 643 70138 D411 T I P S V E E D T W S K T Y A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 95.8 90.4 N.A. 84.6 34.7 N.A. 46.7 31.6 N.A. 66.4 N.A. 34.7 37.2 23.2 37.7
Protein Similarity: 100 99.5 96.4 94.8 N.A. 92.2 51.9 N.A. 55.4 48.6 N.A. 81.2 N.A. 51.5 59.2 40.5 55.9
P-Site Identity: 100 93.3 100 100 N.A. 93.3 6.6 N.A. 6.6 20 N.A. 40 N.A. 6.6 6.6 0 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. 20 46.6 N.A. 80 N.A. 26.6 13.3 33.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. 21.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 38.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 8 0 0 0 0 8 0 0 0 0 50 % A
% Cys: 0 0 0 0 8 0 0 0 0 15 0 0 0 0 0 % C
% Asp: 0 0 0 8 36 0 8 8 15 0 0 8 0 8 8 % D
% Glu: 15 0 0 43 15 15 8 0 0 0 8 0 8 36 0 % E
% Phe: 0 0 8 0 8 0 0 0 0 43 0 0 8 0 8 % F
% Gly: 8 0 0 0 0 8 15 0 0 8 0 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 22 0 15 0 0 8 8 22 0 8 8 0 0 8 % I
% Lys: 0 0 0 0 0 0 15 0 0 0 8 22 8 0 0 % K
% Leu: 15 8 8 8 0 15 0 0 0 8 8 22 0 8 0 % L
% Met: 0 15 0 8 0 0 0 0 0 0 0 36 0 0 0 % M
% Asn: 0 8 8 0 8 0 0 8 0 0 36 8 8 0 0 % N
% Pro: 8 0 8 8 0 36 43 8 0 0 0 0 50 0 0 % P
% Gln: 43 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % Q
% Arg: 8 0 0 0 8 0 8 0 8 0 0 0 0 15 0 % R
% Ser: 0 0 43 15 8 8 0 58 0 0 22 0 15 8 0 % S
% Thr: 8 0 8 0 0 8 0 0 8 8 0 0 8 15 8 % T
% Val: 0 36 15 0 8 0 0 8 43 0 8 0 0 0 8 % V
% Trp: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 8 8 0 0 15 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _