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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: H2AFV All Species: 54.24
Human Site: S99 Identified Species: 74.58
UniProt: Q71UI9 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q71UI9 NP_036544.1 128 13509 S99 R G D E E L D S L I K A T I A
Chimpanzee Pan troglodytes XP_517363 398 42541 S369 R G D E E L D S L I K A T I A
Rhesus Macaque Macaca mulatta XP_001093992 314 32755 S285 R G D E E L D S L I K A T I A
Dog Lupus familis XP_535390 128 13460 S99 P G D E E L D S L I K A T I A
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus P02262 130 14059 L97 N D E E L N K L L G K V T I A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507614 252 26680 S223 R G D E E L D S L I K A T I A
Chicken Gallus gallus P02272 128 13490 S99 R G D E E L D S L I K A T I A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001036788 128 13548 S99 R G D E E L D S L I K A T I A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08985 141 14963 S99 R G D E E L D S L I K A T I A
Honey Bee Apis mellifera XP_624167 155 16370 S126 R G D E E L D S L I K A T I A
Nematode Worm Caenorhab. elegans Q27511 140 14651 T101 R G D E E L D T L I K A T I A
Sea Urchin Strong. purpuratus P08991 125 13146 S96 R G D E E L D S L I K A T I A
Poplar Tree Populus trichocarpa XP_002309600 134 14282 E104 Q L A I R G D E E L D T L I K
Maize Zea mays NP_001141633 138 14579 E108 Q L A I R G D E E L D T L I K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O23628 136 14522 E106 Q L A I R G D E E L D T L I K
Baker's Yeast Sacchar. cerevisiae Q12692 134 14264 S104 R G D D E L D S L I R A T I A
Red Bread Mold Neurospora crassa Q873G4 143 15269 T109 R G D E E L D T L I R A T I A
Conservation
Percent
Protein Identity: 100 31.4 40.7 88.2 N.A. N.A. 61.5 N.A. 50.7 100 N.A. 98.4 N.A. 87.9 80 79.2 93.7
Protein Similarity: 100 31.6 40.7 89.8 N.A. N.A. 72.3 N.A. 50.7 100 N.A. 98.4 N.A. 89.3 80 82.8 93.7
P-Site Identity: 100 100 100 93.3 N.A. N.A. 40 N.A. 100 100 N.A. 100 N.A. 100 100 93.3 100
P-Site Similarity: 100 100 100 93.3 N.A. N.A. 46.6 N.A. 100 100 N.A. 100 N.A. 100 100 100 100
Percent
Protein Identity: 79.1 78.2 N.A. 76.4 63.4 62.9
Protein Similarity: 81.3 81.1 N.A. 81.6 76.1 72.7
P-Site Identity: 13.3 13.3 N.A. 13.3 86.6 86.6
P-Site Similarity: 26.6 26.6 N.A. 26.6 100 100
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 18 0 0 0 0 0 0 0 0 77 0 0 83 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 6 77 6 0 0 95 0 0 0 18 0 0 0 0 % D
% Glu: 0 0 6 77 77 0 0 18 18 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 77 0 0 0 18 0 0 0 6 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 18 0 0 0 0 0 77 0 0 0 100 0 % I
% Lys: 0 0 0 0 0 0 6 0 0 0 71 0 0 0 18 % K
% Leu: 0 18 0 0 6 77 0 6 83 18 0 0 18 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 6 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % N
% Pro: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 18 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 71 0 0 0 18 0 0 0 0 0 12 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 65 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 12 0 0 0 18 83 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _