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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBN3 All Species: 5.45
Human Site: Y312 Identified Species: 15
UniProt: Q75N90 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q75N90 NP_115823.3 2809 300356 Y312 A G D L A G H Y T R R Q C C C
Chimpanzee Pan troglodytes XP_001159724 2859 309524 M341 A Q E L P G R M T K M Q C C C
Rhesus Macaque Macaca mulatta XP_001097964 2618 280636 D270 R G E C I D V D E C T S S P C
Dog Lupus familis XP_542124 2801 297262 Y305 A G D L A G H Y T Q R Q C C C
Cat Felis silvestris
Mouse Mus musculus Q61555 2907 313611 M383 A Q E L P G R M A K A Q C C C
Rat Rattus norvegicus Q00918 1712 186581
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis P21783 2524 275106 Y278 C V D G V N T Y N C Q C P P D
Zebra Danio Brachydanio rerio P46530 2437 262289 D237 G T C V Q T S D T T H T C S C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P07207 2703 288835 C281 G L S Y E C K C P K G F E G K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 67.2 86.3 85.4 N.A. 65.8 22.6 N.A. N.A. N.A. 22.1 22.5 N.A. 21.8 N.A. N.A. N.A.
Protein Similarity: 100 80.1 88.3 90.6 N.A. 78.4 33.3 N.A. N.A. N.A. 35.2 35 N.A. 35.5 N.A. N.A. N.A.
P-Site Identity: 100 53.3 13.3 93.3 N.A. 46.6 0 N.A. N.A. N.A. 13.3 20 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 66.6 20 100 N.A. 60 0 N.A. N.A. N.A. 20 26.6 N.A. 6.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 45 0 0 0 23 0 0 0 12 0 12 0 0 0 0 % A
% Cys: 12 0 12 12 0 12 0 12 0 23 0 12 56 45 67 % C
% Asp: 0 0 34 0 0 12 0 23 0 0 0 0 0 0 12 % D
% Glu: 0 0 34 0 12 0 0 0 12 0 0 0 12 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 12 0 0 0 % F
% Gly: 23 34 0 12 0 45 0 0 0 0 12 0 0 12 0 % G
% His: 0 0 0 0 0 0 23 0 0 0 12 0 0 0 0 % H
% Ile: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 12 0 0 34 0 0 0 0 12 % K
% Leu: 0 12 0 45 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 23 0 0 12 0 0 0 0 % M
% Asn: 0 0 0 0 0 12 0 0 12 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 23 0 0 0 12 0 0 0 12 23 0 % P
% Gln: 0 23 0 0 12 0 0 0 0 12 12 45 0 0 0 % Q
% Arg: 12 0 0 0 0 0 23 0 0 12 23 0 0 0 0 % R
% Ser: 0 0 12 0 0 0 12 0 0 0 0 12 12 12 0 % S
% Thr: 0 12 0 0 0 12 12 0 45 12 12 12 0 0 0 % T
% Val: 0 12 0 12 12 0 12 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 0 0 0 34 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _