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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INTS8
All Species:
31.52
Human Site:
S726
Identified Species:
63.03
UniProt:
Q75QN2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q75QN2
NP_060334.2
995
113088
S726
E
V
V
V
Q
I
C
S
V
S
S
Q
H
K
R
Chimpanzee
Pan troglodytes
XP_519863
1845
206255
S1531
E
V
V
V
Q
I
C
S
V
S
S
Q
H
K
R
Rhesus Macaque
Macaca mulatta
XP_001089895
995
113042
S726
E
V
V
V
Q
I
C
S
V
S
S
Q
H
K
R
Dog
Lupus familis
XP_544184
955
108586
S686
E
V
V
V
Q
I
C
S
V
S
S
Q
H
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80V86
995
113335
S726
E
V
V
V
Q
I
C
S
V
S
N
Q
H
K
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512811
898
102052
R641
H
K
R
G
N
D
G
R
V
S
L
I
K
Q
R
Chicken
Gallus gallus
NP_001035318
995
112926
S726
E
V
V
V
Q
I
C
S
V
S
N
Q
H
K
R
Frog
Xenopus laevis
Q4V847
991
112600
S722
E
V
V
V
Q
I
C
S
V
S
N
Q
H
K
R
Zebra Danio
Brachydanio rerio
NP_001018592
996
113619
S726
E
V
V
V
Q
I
C
S
F
S
S
Q
H
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611162
1007
113462
K734
M
E
K
M
K
G
P
K
K
V
C
R
D
A
W
Honey Bee
Apis mellifera
XP_395965
986
113000
G712
D
M
V
L
T
A
F
G
P
S
R
D
Q
P
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794268
969
109560
Q699
S
I
F
S
T
S
T
Q
T
T
T
Q
T
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.4
99.5
94.4
N.A.
95.7
N.A.
N.A.
84.1
89.4
80.5
69.9
N.A.
24.8
31.2
N.A.
30.1
Protein Similarity:
100
53.1
100
95.6
N.A.
98.6
N.A.
N.A.
87.9
95.1
90.6
82.5
N.A.
46.9
51.6
N.A.
50.9
P-Site Identity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
20
93.3
93.3
93.3
N.A.
0
13.3
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
26.6
100
100
93.3
N.A.
20
40
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
67
0
0
0
9
0
0
0
0
% C
% Asp:
9
0
0
0
0
9
0
0
0
0
0
9
9
0
0
% D
% Glu:
67
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
9
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
9
9
9
0
0
0
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
67
0
0
% H
% Ile:
0
9
0
0
0
67
0
0
0
0
0
9
0
0
0
% I
% Lys:
0
9
9
0
9
0
0
9
9
0
0
0
9
75
0
% K
% Leu:
0
0
0
9
0
0
0
0
0
0
9
0
0
0
0
% L
% Met:
9
9
0
9
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
0
0
0
25
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
9
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
67
0
0
9
0
0
0
75
9
9
9
% Q
% Arg:
0
0
9
0
0
0
0
9
0
0
9
9
0
0
84
% R
% Ser:
9
0
0
9
0
9
0
67
0
84
42
0
0
0
0
% S
% Thr:
0
0
0
0
17
0
9
0
9
9
9
0
9
0
0
% T
% Val:
0
67
75
67
0
0
0
0
67
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _