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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANO5 All Species: 7.88
Human Site: S156 Identified Species: 17.33
UniProt: Q75V66 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q75V66 NP_001136121.1 913 107188 S156 I K M P I K E S D I P R P K H
Chimpanzee Pan troglodytes XP_509014 1130 129847 L371 L P L K P N D L K N R S S A F
Rhesus Macaque Macaca mulatta XP_001092876 910 106164 L151 L P L K P N D L K N R S S A F
Dog Lupus familis XP_542535 1371 157500 S159 I K M P I Q E S D I P P A E T
Cat Felis silvestris
Mouse Mus musculus Q75UR0 904 106195 S148 I K M P I K L S D I P R P K Y
Rat Rattus norvegicus Q6IFT6 860 97152 N139 L P L Q E L P N Q A S N W S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506513 1182 136128 E430 Y K F M S R I E K Q I S R F R
Chicken Gallus gallus XP_001234285 1386 160010 N143 I K V P I R E N D I P S M V E
Frog Xenopus laevis NP_001086810 896 105149 D139 I K M P L K A D D L T D E S E
Zebra Danio Brachydanio rerio Q4V8U5 646 74505
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001073009 921 106692 N167 I K M P I E E N N M E E P V N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 41.3 49.6 51.3 N.A. 80.5 36.7 N.A. 35.4 42.9 61.6 21.3 N.A. N.A. N.A. N.A. 43.2
Protein Similarity: 100 57.9 68.7 57 N.A. 90.4 55.3 N.A. 53.5 53.2 77.7 36.7 N.A. N.A. N.A. N.A. 60.1
P-Site Identity: 100 0 0 66.6 N.A. 86.6 0 N.A. 6.6 53.3 40 0 N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: 100 20 20 80 N.A. 93.3 20 N.A. 13.3 73.3 53.3 0 N.A. N.A. N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 0 10 0 0 10 19 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 19 10 46 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 10 10 37 10 0 0 10 10 10 10 19 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 19 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 55 0 0 0 46 0 10 0 0 37 10 0 0 0 0 % I
% Lys: 0 64 0 19 0 28 0 0 28 0 0 0 0 19 0 % K
% Leu: 28 0 28 0 10 10 10 19 0 10 0 0 0 0 0 % L
% Met: 0 0 46 10 0 0 0 0 0 10 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 19 0 28 10 19 0 10 0 0 10 % N
% Pro: 0 28 0 55 19 0 10 0 0 0 37 10 28 0 0 % P
% Gln: 0 0 0 10 0 10 0 0 10 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 19 0 0 0 0 19 19 10 0 10 % R
% Ser: 0 0 0 0 10 0 0 28 0 0 10 37 19 19 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % T
% Val: 0 0 10 0 0 0 0 0 0 0 0 0 0 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _