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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANO5
All Species:
9.09
Human Site:
S178
Identified Species:
20
UniProt:
Q75V66
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q75V66
NP_001136121.1
913
107188
S178
G
P
V
R
L
P
L
S
V
K
Y
P
H
P
E
Chimpanzee
Pan troglodytes
XP_509014
1130
129847
S393
K
V
L
S
V
D
E
S
I
I
K
P
E
Q
E
Rhesus Macaque
Macaca mulatta
XP_001092876
910
106164
S173
K
V
L
S
V
D
E
S
I
I
K
P
E
Q
E
Dog
Lupus familis
XP_542535
1371
157500
N181
G
P
L
K
L
P
K
N
V
R
H
P
R
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q75UR0
904
106195
S170
G
A
V
K
L
P
S
S
V
K
Y
P
T
P
E
Rat
Rattus norvegicus
Q6IFT6
860
97152
N161
I
P
N
I
L
L
E
N
V
P
D
T
P
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506513
1182
136128
L452
M
R
L
D
K
E
T
L
P
D
L
E
E
N
D
Chicken
Gallus gallus
XP_001234285
1386
160010
K165
T
P
F
R
L
P
E
K
V
M
H
P
E
P
D
Frog
Xenopus laevis
NP_001086810
896
105149
E161
K
P
F
K
L
P
P
E
V
M
S
P
E
P
D
Zebra Danio
Brachydanio rerio
Q4V8U5
646
74505
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001073009
921
106692
S189
L
W
T
P
F
E
L
S
E
E
Y
V
K
P
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.3
49.6
51.3
N.A.
80.5
36.7
N.A.
35.4
42.9
61.6
21.3
N.A.
N.A.
N.A.
N.A.
43.2
Protein Similarity:
100
57.9
68.7
57
N.A.
90.4
55.3
N.A.
53.5
53.2
77.7
36.7
N.A.
N.A.
N.A.
N.A.
60.1
P-Site Identity:
100
20
20
53.3
N.A.
73.3
33.3
N.A.
0
46.6
40
0
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
40
40
86.6
N.A.
80
40
N.A.
13.3
60
53.3
0
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
19
0
0
0
10
10
0
0
0
28
% D
% Glu:
0
0
0
0
0
19
37
10
10
10
0
10
46
0
64
% E
% Phe:
0
0
19
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
28
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
19
0
10
0
0
% H
% Ile:
10
0
0
10
0
0
0
0
19
19
0
0
0
0
0
% I
% Lys:
28
0
0
28
10
0
10
10
0
19
19
0
10
0
0
% K
% Leu:
10
0
37
0
55
10
19
10
0
0
10
0
0
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
19
0
0
0
0
0
10
0
% N
% Pro:
0
46
0
10
0
46
10
0
10
10
0
64
10
64
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% Q
% Arg:
0
10
0
19
0
0
0
0
0
10
0
0
10
0
0
% R
% Ser:
0
0
0
19
0
0
10
46
0
0
10
0
0
0
0
% S
% Thr:
10
0
10
0
0
0
10
0
0
0
0
10
10
0
0
% T
% Val:
0
19
19
0
19
0
0
0
55
0
0
10
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
28
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _