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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANO5
All Species:
23.64
Human Site:
S555
Identified Species:
52
UniProt:
Q75V66
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q75V66
NP_001136121.1
913
107188
S555
T
Y
Q
E
Y
E
S
S
L
T
L
K
M
F
L
Chimpanzee
Pan troglodytes
XP_509014
1130
129847
S769
T
Q
T
D
Y
E
N
S
L
T
M
K
M
F
L
Rhesus Macaque
Macaca mulatta
XP_001092876
910
106164
S549
T
Q
T
D
Y
E
N
S
L
T
M
K
M
F
L
Dog
Lupus familis
XP_542535
1371
157500
S576
T
Y
Q
E
Y
E
S
S
L
T
L
K
M
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q75UR0
904
106195
S546
T
H
Q
E
Y
E
S
S
L
T
L
K
M
F
L
Rat
Rattus norvegicus
Q6IFT6
860
97152
A528
T
Q
T
A
F
E
D
A
F
T
L
K
V
F
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506513
1182
136128
S818
T
E
S
E
W
E
N
S
F
T
L
K
M
F
L
Chicken
Gallus gallus
XP_001234285
1386
160010
R595
T
H
M
E
Y
E
N
R
L
T
M
K
M
F
L
Frog
Xenopus laevis
NP_001086810
896
105149
R536
T
H
L
E
Y
E
N
R
L
T
M
K
M
F
L
Zebra Danio
Brachydanio rerio
Q4V8U5
646
74505
F330
L
L
C
L
Y
L
S
F
Y
V
M
M
V
Y
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001073009
921
106692
S557
T
E
T
E
Y
E
D
S
F
T
F
K
M
Y
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.3
49.6
51.3
N.A.
80.5
36.7
N.A.
35.4
42.9
61.6
21.3
N.A.
N.A.
N.A.
N.A.
43.2
Protein Similarity:
100
57.9
68.7
57
N.A.
90.4
55.3
N.A.
53.5
53.2
77.7
36.7
N.A.
N.A.
N.A.
N.A.
60.1
P-Site Identity:
100
66.6
66.6
100
N.A.
93.3
40
N.A.
66.6
66.6
66.6
13.3
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
86.6
86.6
100
N.A.
100
66.6
N.A.
80
86.6
86.6
33.3
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
0
0
19
0
0
0
0
0
0
0
0
% D
% Glu:
0
19
0
64
0
91
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
10
28
0
10
0
0
82
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
28
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
91
0
0
0
% K
% Leu:
10
10
10
10
0
10
0
0
64
0
46
0
0
0
82
% L
% Met:
0
0
10
0
0
0
0
0
0
0
46
10
82
0
0
% M
% Asn:
0
0
0
0
0
0
46
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
28
28
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
37
64
0
0
0
0
0
0
0
% S
% Thr:
91
0
37
0
0
0
0
0
0
91
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
19
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
19
0
0
82
0
0
0
10
0
0
0
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _