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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANO5
All Species:
1.21
Human Site:
T164
Identified Species:
2.67
UniProt:
Q75V66
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q75V66
NP_001136121.1
913
107188
T164
D
I
P
R
P
K
H
T
P
I
S
Y
V
L
G
Chimpanzee
Pan troglodytes
XP_509014
1130
129847
G379
K
N
R
S
S
A
F
G
T
L
N
W
F
T
K
Rhesus Macaque
Macaca mulatta
XP_001092876
910
106164
G159
K
N
R
S
S
A
F
G
T
L
N
W
F
T
K
Dog
Lupus familis
XP_542535
1371
157500
F167
D
I
P
P
A
E
T
F
P
F
S
Y
M
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q75UR0
904
106195
P156
D
I
P
R
P
K
Y
P
P
L
S
Y
M
L
G
Rat
Rattus norvegicus
Q6IFT6
860
97152
T147
Q
A
S
N
W
S
A
T
L
L
E
W
L
G
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506513
1182
136128
R438
K
Q
I
S
R
F
R
R
W
L
P
R
K
P
M
Chicken
Gallus gallus
XP_001234285
1386
160010
N151
D
I
P
S
M
V
E
N
P
L
D
C
M
L
T
Frog
Xenopus laevis
NP_001086810
896
105149
N147
D
L
T
D
E
S
E
N
L
L
S
H
M
L
K
Zebra Danio
Brachydanio rerio
Q4V8U5
646
74505
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001073009
921
106692
V175
N
M
E
E
P
V
N
V
F
N
C
I
D
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.3
49.6
51.3
N.A.
80.5
36.7
N.A.
35.4
42.9
61.6
21.3
N.A.
N.A.
N.A.
N.A.
43.2
Protein Similarity:
100
57.9
68.7
57
N.A.
90.4
55.3
N.A.
53.5
53.2
77.7
36.7
N.A.
N.A.
N.A.
N.A.
60.1
P-Site Identity:
100
0
0
53.3
N.A.
73.3
6.6
N.A.
0
33.3
20
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
20
66.6
N.A.
93.3
26.6
N.A.
6.6
46.6
46.6
0
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
19
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% C
% Asp:
46
0
0
10
0
0
0
0
0
0
10
0
10
0
0
% D
% Glu:
0
0
10
10
10
10
19
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
19
10
10
10
0
0
19
0
0
% F
% Gly:
0
0
0
0
0
0
0
19
0
0
0
0
0
10
28
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% H
% Ile:
0
37
10
0
0
0
0
0
0
10
0
10
0
0
10
% I
% Lys:
28
0
0
0
0
19
0
0
0
0
0
0
10
10
28
% K
% Leu:
0
10
0
0
0
0
0
0
19
64
0
0
10
46
10
% L
% Met:
0
10
0
0
10
0
0
0
0
0
0
0
37
0
10
% M
% Asn:
10
19
0
10
0
0
10
19
0
10
19
0
0
0
0
% N
% Pro:
0
0
37
10
28
0
0
10
37
0
10
0
0
10
0
% P
% Gln:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
19
19
10
0
10
10
0
0
0
10
0
0
0
% R
% Ser:
0
0
10
37
19
19
0
0
0
0
37
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
10
19
19
0
0
0
0
19
10
% T
% Val:
0
0
0
0
0
19
0
10
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
10
0
0
28
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
28
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _