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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANO5
All Species:
16.97
Human Site:
Y296
Identified Species:
37.33
UniProt:
Q75V66
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q75V66
NP_001136121.1
913
107188
Y296
L
D
L
I
K
N
Y
Y
G
E
K
I
G
I
Y
Chimpanzee
Pan troglodytes
XP_509014
1130
129847
Y511
L
D
L
I
R
K
Y
Y
G
E
K
I
G
I
Y
Rhesus Macaque
Macaca mulatta
XP_001092876
910
106164
Y291
L
D
L
I
R
K
Y
Y
G
E
K
I
G
I
Y
Dog
Lupus familis
XP_542535
1371
157500
F299
L
D
L
V
R
N
Y
F
G
E
K
I
A
M
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q75UR0
904
106195
F287
F
H
L
I
R
N
Y
F
G
E
K
I
G
I
Y
Rat
Rattus norvegicus
Q6IFT6
860
97152
F281
L
D
H
V
R
R
Y
F
G
E
K
V
A
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506513
1182
136128
F570
L
D
L
V
R
R
Y
F
G
E
K
I
G
L
Y
Chicken
Gallus gallus
XP_001234285
1386
160010
Y318
L
D
L
I
R
K
Y
Y
G
E
K
I
G
I
Y
Frog
Xenopus laevis
NP_001086810
896
105149
Y277
L
D
L
I
R
K
Y
Y
G
E
K
I
G
I
Y
Zebra Danio
Brachydanio rerio
Q4V8U5
646
74505
R98
E
F
Q
D
G
T
M
R
G
F
T
Y
A
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001073009
921
106692
F310
L
D
L
I
R
R
Y
F
G
E
K
I
G
I
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.3
49.6
51.3
N.A.
80.5
36.7
N.A.
35.4
42.9
61.6
21.3
N.A.
N.A.
N.A.
N.A.
43.2
Protein Similarity:
100
57.9
68.7
57
N.A.
90.4
55.3
N.A.
53.5
53.2
77.7
36.7
N.A.
N.A.
N.A.
N.A.
60.1
P-Site Identity:
100
86.6
86.6
66.6
N.A.
73.3
46.6
N.A.
66.6
86.6
86.6
6.6
N.A.
N.A.
N.A.
N.A.
80
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
86.6
80
N.A.
93.3
93.3
93.3
6.6
N.A.
N.A.
N.A.
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
82
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
91
0
0
0
0
0
% E
% Phe:
10
10
0
0
0
0
0
46
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
100
0
0
0
73
0
0
% G
% His:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
64
0
0
0
0
0
0
0
82
0
64
0
% I
% Lys:
0
0
0
0
10
37
0
0
0
0
91
0
0
0
0
% K
% Leu:
82
0
82
0
0
0
0
0
0
0
0
0
0
19
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
28
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
82
28
0
10
0
0
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
28
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
91
46
0
0
0
10
0
0
91
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _