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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANO5
All Species:
30.61
Human Site:
Y761
Identified Species:
67.33
UniProt:
Q75V66
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q75V66
NP_001136121.1
913
107188
Y761
D
I
I
P
R
L
V
Y
Y
Y
A
Y
S
T
N
Chimpanzee
Pan troglodytes
XP_509014
1130
129847
Y975
D
M
I
P
R
L
V
Y
Y
W
S
F
S
V
P
Rhesus Macaque
Macaca mulatta
XP_001092876
910
106164
Y755
D
M
I
P
R
L
V
Y
Y
W
S
F
S
V
P
Dog
Lupus familis
XP_542535
1371
157500
Y782
D
I
I
P
R
L
V
Y
Y
Y
A
Y
S
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q75UR0
904
106195
Y752
D
I
I
P
R
L
V
Y
F
Y
A
Y
S
T
N
Rat
Rattus norvegicus
Q6IFT6
860
97152
Y734
D
F
L
P
R
V
Y
Y
S
W
T
R
A
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506513
1182
136128
Y1028
D
F
I
P
R
L
V
Y
A
Y
K
Y
G
P
C
Chicken
Gallus gallus
XP_001234285
1386
160010
Y801
D
M
I
P
R
L
V
Y
Y
Y
A
Y
S
E
S
Frog
Xenopus laevis
NP_001086810
896
105149
Y742
D
M
I
P
R
L
V
Y
Y
Y
A
Y
T
Q
D
Zebra Danio
Brachydanio rerio
Q4V8U5
646
74505
I527
V
L
V
V
L
N
N
I
T
E
V
Y
S
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001073009
921
106692
F766
E
F
I
P
R
Q
V
F
K
Y
Y
Y
G
G
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.3
49.6
51.3
N.A.
80.5
36.7
N.A.
35.4
42.9
61.6
21.3
N.A.
N.A.
N.A.
N.A.
43.2
Protein Similarity:
100
57.9
68.7
57
N.A.
90.4
55.3
N.A.
53.5
53.2
77.7
36.7
N.A.
N.A.
N.A.
N.A.
60.1
P-Site Identity:
100
60
60
86.6
N.A.
93.3
26.6
N.A.
60
80
73.3
13.3
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
86.6
86.6
93.3
N.A.
100
60
N.A.
60
93.3
93.3
26.6
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
46
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
82
0
0
0
0
0
0
0
0
0
0
0
0
10
28
% D
% Glu:
10
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% E
% Phe:
0
28
0
0
0
0
0
10
10
0
0
19
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
19
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
28
82
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
10
0
0
10
0
% K
% Leu:
0
10
10
0
10
73
0
0
0
0
0
0
0
0
0
% L
% Met:
0
37
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
19
% N
% Pro:
0
0
0
91
0
0
0
0
0
0
0
0
0
19
28
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
91
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
10
0
19
0
64
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
10
0
10
0
10
19
0
% T
% Val:
10
0
10
10
0
10
82
0
0
0
10
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
28
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
82
55
64
10
73
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _