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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM5C
All Species:
26.97
Human Site:
S418
Identified Species:
84.76
UniProt:
Q76B58
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q76B58
NP_950252.1
766
88445
S418
N
E
N
G
L
L
G
S
F
S
E
E
T
H
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113122
766
88439
S418
N
E
N
G
L
L
G
S
F
S
E
E
T
H
S
Dog
Lupus familis
XP_536117
766
88411
S418
N
E
N
G
L
L
G
S
F
S
E
E
T
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q499E0
766
88465
S418
N
E
N
G
L
L
G
S
F
S
E
E
T
H
S
Rat
Rattus norvegicus
Q8K1M7
766
88479
S418
N
E
N
G
L
L
G
S
F
S
E
E
T
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516377
799
91882
S451
N
E
N
G
L
L
G
S
F
S
E
E
T
H
S
Chicken
Gallus gallus
Q7ZZR3
761
88774
S409
F
W
G
T
F
L
E
S
Q
R
S
C
V
C
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001341569
797
91064
S449
S
E
N
N
Q
L
G
S
F
S
E
E
L
H
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.6
98.5
N.A.
97.7
97.6
N.A.
91.9
54.3
N.A.
74.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
99.7
99.4
N.A.
99.2
98.9
N.A.
93.4
71.8
N.A.
85.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
13.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
13.3
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
13
0
13
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
88
0
0
0
0
13
0
0
0
88
88
0
0
0
% E
% Phe:
13
0
0
0
13
0
0
0
88
0
0
0
0
0
0
% F
% Gly:
0
0
13
75
0
0
88
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
88
13
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
75
100
0
0
0
0
0
0
13
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
75
0
88
13
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
13
0
0
0
13
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% R
% Ser:
13
0
0
0
0
0
0
100
0
88
13
0
0
0
75
% S
% Thr:
0
0
0
13
0
0
0
0
0
0
0
0
75
0
13
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% V
% Trp:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _