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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM5C All Species: 22.73
Human Site: S545 Identified Species: 71.43
UniProt: Q76B58 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q76B58 NP_950252.1 766 88445 S545 K S N K Y K S S L V H M I L G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001113122 766 88439 S545 K S N K Y K S S L V H M I L G
Dog Lupus familis XP_536117 766 88411 S545 K S N K Y K S S L V H M I L G
Cat Felis silvestris
Mouse Mus musculus Q499E0 766 88465 S545 K S N K Y K S S L V H M I L G
Rat Rattus norvegicus Q8K1M7 766 88479 S545 K S N K Y K S S L V H M I L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516377 799 91882 S578 K S N K Y K S S L V H M I L G
Chicken Gallus gallus Q7ZZR3 761 88774 D536 K S N K N R M D F I H M V I G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001341569 797 91064 N576 K S N K Y K S N L V H M L L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.6 98.5 N.A. 97.7 97.6 N.A. 91.9 54.3 N.A. 74.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 99.7 99.4 N.A. 99.2 98.9 N.A. 93.4 71.8 N.A. 85.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 46.6 N.A. 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 100 73.3 N.A. 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % G
% His: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 13 0 0 75 13 0 % I
% Lys: 100 0 0 100 0 88 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 88 0 0 0 13 88 0 % L
% Met: 0 0 0 0 0 0 13 0 0 0 0 100 0 0 0 % M
% Asn: 0 0 100 0 13 0 0 13 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 100 0 0 0 0 88 75 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 88 0 0 13 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 88 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _