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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM5C All Species: 25.15
Human Site: Y409 Identified Species: 79.05
UniProt: Q76B58 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q76B58 NP_950252.1 766 88445 Y409 T R I Q S F L Y C N E N G L L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001113122 766 88439 Y409 T R I Q S F L Y C N E N G L L
Dog Lupus familis XP_536117 766 88411 Y409 T R I Q S F L Y C N E N G L L
Cat Felis silvestris
Mouse Mus musculus Q499E0 766 88465 Y409 T R I Q S F L Y C N E N G L L
Rat Rattus norvegicus Q8K1M7 766 88479 Y409 T R I Q S F L Y C N E N G L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516377 799 91882 Y442 N R I Q S F L Y C N E N G L L
Chicken Gallus gallus Q7ZZR3 761 88774 N400 S L L Y C N E N G F W G T F L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001341569 797 91064 Y440 N Y F Q S L L Y C S E N N Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.6 98.5 N.A. 97.7 97.6 N.A. 91.9 54.3 N.A. 74.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 99.7 99.4 N.A. 99.2 98.9 N.A. 93.4 71.8 N.A. 85.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 93.3 6.6 N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 93.3 20 N.A. 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 13 0 0 0 88 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 13 0 0 0 88 0 0 0 0 % E
% Phe: 0 0 13 0 0 75 0 0 0 13 0 0 0 13 0 % F
% Gly: 0 0 0 0 0 0 0 0 13 0 0 13 75 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 75 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 13 13 0 0 13 88 0 0 0 0 0 0 75 100 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 25 0 0 0 0 13 0 13 0 75 0 88 13 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 88 0 0 0 0 0 0 0 0 0 13 0 % Q
% Arg: 0 75 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 13 0 0 0 88 0 0 0 0 13 0 0 0 0 0 % S
% Thr: 63 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % W
% Tyr: 0 13 0 13 0 0 0 88 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _