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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDZD4
All Species:
9.09
Human Site:
Y354
Identified Species:
28.57
UniProt:
Q76G19
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q76G19
NP_115901.2
769
86171
Y354
P
G
L
T
D
E
E
Y
E
R
Y
R
E
L
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087147
673
75469
C317
L
R
H
L
E
F
K
C
R
N
I
L
R
A
Q
Dog
Lupus familis
XP_853448
762
85054
L352
Y
E
R
Y
R
E
L
L
E
I
K
G
H
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QY39
772
86800
Y359
P
G
L
T
D
E
E
Y
E
R
Y
R
E
L
L
Rat
Rattus norvegicus
P68907
1062
119270
C642
L
G
I
P
E
D
E
C
E
R
F
R
E
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511227
786
87739
Y345
P
G
L
T
D
E
E
Y
E
R
Y
R
E
L
L
Chicken
Gallus gallus
XP_414432
1060
119396
C642
L
G
I
P
V
D
E
C
E
R
F
R
E
L
L
Frog
Xenopus laevis
NP_001090510
1029
116923
R613
M
D
E
C
E
R
F
R
E
L
L
E
L
K
C
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
86.2
92.7
N.A.
92.6
37.7
N.A.
84.7
39.8
38
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
86.3
94.2
N.A.
95.3
50.2
N.A.
89
51.4
51.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
0
20
N.A.
100
53.3
N.A.
100
53.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
13.3
20
N.A.
100
80
N.A.
100
73.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% A
% Cys:
0
0
0
13
0
0
0
38
0
0
0
0
0
0
13
% C
% Asp:
0
13
0
0
38
25
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
13
13
0
38
50
63
0
88
0
0
13
63
0
13
% E
% Phe:
0
0
0
0
0
13
13
0
0
0
25
0
0
0
0
% F
% Gly:
0
63
0
0
0
0
0
0
0
0
0
13
0
0
0
% G
% His:
0
0
13
0
0
0
0
0
0
0
0
0
13
0
0
% H
% Ile:
0
0
25
0
0
0
0
0
0
13
13
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
13
0
0
0
13
0
0
13
0
% K
% Leu:
38
0
38
13
0
0
13
13
0
13
13
13
13
75
63
% L
% Met:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% N
% Pro:
38
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% Q
% Arg:
0
13
13
0
13
13
0
13
13
63
0
63
13
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
38
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
13
0
0
0
38
0
0
38
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _