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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SSH2 All Species: 20.3
Human Site: S637 Identified Species: 49.63
UniProt: Q76I76 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q76I76 NP_203747.2 1423 158216 S637 E S P S P Q P S C Q T E I S D
Chimpanzee Pan troglodytes XP_511379 1430 158848 S644 E S P S P Q P S C Q T E I S D
Rhesus Macaque Macaca mulatta XP_001111434 1430 158674 S644 E S P S P Q P S C Q T E I S D
Dog Lupus familis XP_548303 1421 157709 S644 E S P S P Q P S C Q A E V S D
Cat Felis silvestris
Mouse Mus musculus Q5SW75 1423 158212 S637 E S P S P Q A S C Q A A I S D
Rat Rattus norvegicus NP_001100494 1430 159245 G644 E S P S P Q A G C Q A A I S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510076 1531 167423 S774 L P A S P D P S S P S P Q P C
Chicken Gallus gallus XP_415832 1338 147922 S580 D A N V I K E S C V K E R R I
Frog Xenopus laevis Q6IVY4 691 78886
Zebra Danio Brachydanio rerio XP_001921323 1168 129511 G414 A Y A M K E Y G W D L D R A F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.7 95 83.8 N.A. 83.6 79.7 N.A. 61.5 61.1 27.2 44.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.1 95.9 88.7 N.A. 89.3 86 N.A. 68.9 70.1 35.5 56.4 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 80 73.3 N.A. 26.6 20 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 80 73.3 N.A. 33.3 40 0 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 20 0 0 0 20 0 0 0 30 20 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 70 0 0 0 0 0 10 % C
% Asp: 10 0 0 0 0 10 0 0 0 10 0 10 0 0 60 % D
% Glu: 60 0 0 0 0 10 10 0 0 0 0 50 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 0 50 0 10 % I
% Lys: 0 0 0 0 10 10 0 0 0 0 10 0 0 0 0 % K
% Leu: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 60 0 70 0 50 0 0 10 0 10 0 10 0 % P
% Gln: 0 0 0 0 0 60 0 0 0 60 0 0 10 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 20 10 0 % R
% Ser: 0 60 0 70 0 0 0 70 10 0 10 0 0 60 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 30 0 0 0 0 % T
% Val: 0 0 0 10 0 0 0 0 0 10 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _