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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN2
All Species:
14.24
Human Site:
S268
Identified Species:
34.81
UniProt:
Q76MJ5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q76MJ5
NP_150296.3
926
102466
S268
G
H
I
R
L
P
A
S
G
P
Q
D
T
A
T
Chimpanzee
Pan troglodytes
XP_510880
974
107065
S316
G
H
I
R
L
P
A
S
G
P
Q
D
T
A
T
Rhesus Macaque
Macaca mulatta
XP_001089227
820
89327
Y233
W
N
T
T
Y
R
R
Y
S
A
P
P
M
D
G
Dog
Lupus familis
XP_547090
925
102471
S264
G
H
I
R
L
P
A
S
G
P
Q
H
T
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2E3
911
101337
S267
G
H
I
R
L
P
A
S
S
Y
Q
D
T
A
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505283
1129
123221
S267
I
R
L
A
H
W
R
S
P
P
D
P
A
N
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392044
968
110555
N288
L
I
L
K
R
F
A
N
K
P
S
D
I
Q
L
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
V278
T
V
D
Q
W
P
T
V
L
G
V
N
A
A
D
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
Y283
H
L
L
D
G
G
E
Y
P
T
W
R
N
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
R330
G
M
C
I
A
P
F
R
D
K
S
L
L
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.2
77.6
84.2
N.A.
80.5
N.A.
N.A.
53.5
N.A.
N.A.
N.A.
N.A.
N.A.
38.4
37.4
36
Protein Similarity:
100
94.4
79.5
88.9
N.A.
86.2
N.A.
N.A.
61.8
N.A.
N.A.
N.A.
N.A.
N.A.
54.3
54.5
48.2
P-Site Identity:
100
100
0
93.3
N.A.
86.6
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
20
13.3
0
P-Site Similarity:
100
100
6.6
93.3
N.A.
86.6
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
40
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
50
0
0
10
0
0
20
60
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
0
0
0
0
10
0
10
40
0
10
10
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
0
0
10
10
0
0
30
10
0
0
0
0
20
% G
% His:
10
40
0
0
10
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
10
10
40
10
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
10
10
0
0
0
0
0
% K
% Leu:
10
10
30
0
40
0
0
0
10
0
0
10
10
0
20
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
0
0
0
0
0
10
0
0
0
10
10
10
0
% N
% Pro:
0
0
0
0
0
60
0
0
20
50
10
20
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
40
0
0
20
0
% Q
% Arg:
0
10
0
40
10
10
20
10
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
50
20
0
20
0
0
0
10
% S
% Thr:
10
0
10
10
0
0
10
0
0
10
0
0
40
0
40
% T
% Val:
0
10
0
0
0
0
0
10
0
0
10
0
0
0
0
% V
% Trp:
10
0
0
0
10
10
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
20
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _