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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN2
All Species:
5.45
Human Site:
S424
Identified Species:
13.33
UniProt:
Q76MJ5
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q76MJ5
NP_150296.3
926
102466
S424
P
E
E
K
T
P
D
S
Y
L
G
L
G
P
Q
Chimpanzee
Pan troglodytes
XP_510880
974
107065
S472
P
E
E
K
T
P
D
S
Y
L
G
L
G
P
Q
Rhesus Macaque
Macaca mulatta
XP_001089227
820
89327
P388
S
G
E
R
E
G
S
P
S
T
A
V
R
Y
P
Dog
Lupus familis
XP_547090
925
102471
L420
P
E
E
K
T
P
D
L
Y
P
G
L
G
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2E3
911
101337
G423
K
A
S
D
S
Y
P
G
L
G
S
Q
D
L
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505283
1129
123221
L429
P
A
A
G
R
T
E
L
S
P
Q
P
G
P
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392044
968
110555
K445
W
F
S
Q
Q
E
N
K
G
L
K
L
T
L
I
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
N433
S
F
I
L
L
L
L
N
N
H
P
I
P
F
Y
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
E441
L
W
W
V
N
R
S
E
A
V
F
M
G
G
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
Y536
L
K
F
G
S
L
V
Y
R
I
I
E
T
G
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.2
77.6
84.2
N.A.
80.5
N.A.
N.A.
53.5
N.A.
N.A.
N.A.
N.A.
N.A.
38.4
37.4
36
Protein Similarity:
100
94.4
79.5
88.9
N.A.
86.2
N.A.
N.A.
61.8
N.A.
N.A.
N.A.
N.A.
N.A.
54.3
54.5
48.2
P-Site Identity:
100
100
6.6
86.6
N.A.
0
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
0
6.6
P-Site Similarity:
100
100
20
86.6
N.A.
6.6
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
10
0
0
0
0
0
10
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
30
0
0
0
0
0
10
0
0
% D
% Glu:
0
30
40
0
10
10
10
10
0
0
0
10
0
0
0
% E
% Phe:
0
20
10
0
0
0
0
0
0
0
10
0
0
10
0
% F
% Gly:
0
10
0
20
0
10
0
10
10
10
30
0
50
20
10
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
10
10
10
0
0
20
% I
% Lys:
10
10
0
30
0
0
0
10
0
0
10
0
0
0
0
% K
% Leu:
20
0
0
10
10
20
10
20
10
30
0
40
0
20
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
10
0
10
10
10
0
0
0
0
0
0
% N
% Pro:
40
0
0
0
0
30
10
10
0
20
10
10
10
40
10
% P
% Gln:
0
0
0
10
10
0
0
0
0
0
10
10
0
0
30
% Q
% Arg:
0
0
0
10
10
10
0
0
10
0
0
0
10
0
0
% R
% Ser:
20
0
20
0
20
0
20
20
20
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
30
10
0
0
0
10
0
0
20
0
0
% T
% Val:
0
0
0
10
0
0
10
0
0
10
0
10
0
0
10
% V
% Trp:
10
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
10
30
0
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _