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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN2
All Species:
7.58
Human Site:
S481
Identified Species:
18.52
UniProt:
Q76MJ5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q76MJ5
NP_150296.3
926
102466
S481
H
I
S
Q
D
A
Q
S
L
H
S
G
A
T
R
Chimpanzee
Pan troglodytes
XP_510880
974
107065
S529
H
I
S
Q
D
A
Q
S
L
H
S
G
A
T
R
Rhesus Macaque
Macaca mulatta
XP_001089227
820
89327
D434
T
P
G
S
G
T
A
D
T
R
P
P
E
N
T
Dog
Lupus familis
XP_547090
925
102471
P479
H
I
S
H
N
A
Q
P
L
P
S
G
A
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2E3
911
101337
G469
D
L
S
Q
D
A
Q
G
Q
L
S
R
D
I
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505283
1129
123221
P489
I
S
W
Q
D
V
A
P
L
S
S
L
S
S
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392044
968
110555
A495
Y
Y
G
T
R
S
N
A
L
V
V
P
E
D
M
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
P479
S
F
E
I
V
N
N
P
G
E
S
R
S
A
Q
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
S474
V
V
V
S
S
S
P
S
E
S
S
Q
H
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
S635
A
D
E
D
D
E
K
S
L
D
L
T
T
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.2
77.6
84.2
N.A.
80.5
N.A.
N.A.
53.5
N.A.
N.A.
N.A.
N.A.
N.A.
38.4
37.4
36
Protein Similarity:
100
94.4
79.5
88.9
N.A.
86.2
N.A.
N.A.
61.8
N.A.
N.A.
N.A.
N.A.
N.A.
54.3
54.5
48.2
P-Site Identity:
100
100
0
66.6
N.A.
40
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
6.6
13.3
P-Site Similarity:
100
100
0
73.3
N.A.
46.6
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
40
20
10
0
0
0
0
30
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
10
50
0
0
10
0
10
0
0
10
10
0
% D
% Glu:
0
0
20
0
0
10
0
0
10
10
0
0
20
10
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
20
0
10
0
0
10
10
0
0
30
0
0
10
% G
% His:
30
0
0
10
0
0
0
0
0
20
0
0
10
0
0
% H
% Ile:
10
30
0
10
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% K
% Leu:
0
10
0
0
0
0
0
0
60
10
10
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
10
10
20
0
0
0
0
0
0
10
0
% N
% Pro:
0
10
0
0
0
0
10
30
0
10
10
20
0
0
0
% P
% Gln:
0
0
0
40
0
0
40
0
10
0
0
10
0
0
10
% Q
% Arg:
0
0
0
0
10
0
0
0
0
10
0
20
0
0
30
% R
% Ser:
10
10
40
20
10
20
0
40
0
20
70
0
20
20
10
% S
% Thr:
10
0
0
10
0
10
0
0
10
0
0
10
10
30
10
% T
% Val:
10
10
10
0
10
10
0
0
0
10
10
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _