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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN2
All Species:
7.88
Human Site:
S496
Identified Species:
19.26
UniProt:
Q76MJ5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q76MJ5
NP_150296.3
926
102466
S496
R
S
Q
K
R
L
Q
S
P
S
K
Q
A
Q
P
Chimpanzee
Pan troglodytes
XP_510880
974
107065
S544
R
S
Q
K
R
F
Q
S
P
S
K
Q
A
Q
P
Rhesus Macaque
Macaca mulatta
XP_001089227
820
89327
E449
Q
T
P
A
F
F
L
E
L
L
S
L
S
R
E
Dog
Lupus familis
XP_547090
925
102471
N494
Q
G
Q
K
S
L
P
N
S
P
E
Q
A
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2E3
911
101337
S484
Q
D
Q
R
R
F
Q
S
P
S
E
P
A
Q
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505283
1129
123221
C504
T
D
Q
I
S
S
R
C
P
L
G
N
P
A
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392044
968
110555
G510
G
E
G
V
V
K
V
G
K
I
T
F
D
T
G
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
G494
T
S
K
Q
S
N
R
G
S
F
G
W
A
N
R
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
R566
T
G
S
T
G
G
K
R
D
V
S
V
T
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
R650
K
K
R
K
R
G
S
R
G
G
K
K
G
R
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.2
77.6
84.2
N.A.
80.5
N.A.
N.A.
53.5
N.A.
N.A.
N.A.
N.A.
N.A.
38.4
37.4
36
Protein Similarity:
100
94.4
79.5
88.9
N.A.
86.2
N.A.
N.A.
61.8
N.A.
N.A.
N.A.
N.A.
N.A.
54.3
54.5
48.2
P-Site Identity:
100
93.3
0
40
N.A.
60
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
0
13.3
0
P-Site Similarity:
100
93.3
26.6
60
N.A.
80
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
0
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
0
0
50
10
10
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
0
0
0
0
0
10
0
0
0
10
0
0
% D
% Glu:
0
10
0
0
0
0
0
10
0
0
20
0
0
0
10
% E
% Phe:
0
0
0
0
10
30
0
0
0
10
0
10
0
0
0
% F
% Gly:
10
20
10
0
10
20
0
20
10
10
20
0
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
10
10
10
40
0
10
10
0
10
0
30
10
0
0
10
% K
% Leu:
0
0
0
0
0
20
10
0
10
20
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
10
0
0
0
10
0
10
0
% N
% Pro:
0
0
10
0
0
0
10
0
40
10
0
10
10
10
30
% P
% Gln:
30
0
50
10
0
0
30
0
0
0
0
30
0
40
0
% Q
% Arg:
20
0
10
10
40
0
20
20
0
0
0
0
0
20
20
% R
% Ser:
0
30
10
0
30
10
10
30
20
30
20
0
10
0
0
% S
% Thr:
30
10
0
10
0
0
0
0
0
0
10
0
10
10
0
% T
% Val:
0
0
0
10
10
0
10
0
0
10
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _