KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN2
All Species:
20.61
Human Site:
T181
Identified Species:
50.37
UniProt:
Q76MJ5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q76MJ5
NP_150296.3
926
102466
T181
P
A
L
R
W
N
T
T
Y
R
R
Y
S
A
P
Chimpanzee
Pan troglodytes
XP_510880
974
107065
T229
P
A
L
R
W
N
T
T
Y
R
R
Y
S
A
P
Rhesus Macaque
Macaca mulatta
XP_001089227
820
89327
Q147
I
L
G
T
Q
K
Q
Q
G
L
M
K
L
P
F
Dog
Lupus familis
XP_547090
925
102471
T177
P
A
L
R
W
N
I
T
Y
R
R
Y
S
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2E3
911
101337
T180
P
A
L
R
W
N
T
T
Y
R
R
Y
S
A
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505283
1129
123221
T178
R
E
L
R
W
N
V
T
Y
H
D
Y
S
A
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392044
968
110555
K198
I
M
V
D
S
K
Q
K
N
R
K
W
N
V
T
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
T190
R
G
K
T
W
N
A
T
F
N
D
Y
S
A
H
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
S195
T
M
F
D
S
T
N
S
N
K
I
W
N
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
S215
T
N
I
V
V
N
D
S
G
K
I
V
E
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.2
77.6
84.2
N.A.
80.5
N.A.
N.A.
53.5
N.A.
N.A.
N.A.
N.A.
N.A.
38.4
37.4
36
Protein Similarity:
100
94.4
79.5
88.9
N.A.
86.2
N.A.
N.A.
61.8
N.A.
N.A.
N.A.
N.A.
N.A.
54.3
54.5
48.2
P-Site Identity:
100
100
0
86.6
N.A.
100
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
40
0
P-Site Similarity:
100
100
0
86.6
N.A.
100
N.A.
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
46.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
40
0
0
0
0
10
0
0
0
0
0
0
60
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
20
0
0
10
0
0
0
20
0
0
10
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
10
% E
% Phe:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
10
% F
% Gly:
0
10
10
0
0
0
0
0
20
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% H
% Ile:
20
0
10
0
0
0
10
0
0
0
20
0
0
0
0
% I
% Lys:
0
0
10
0
0
20
0
10
0
20
10
10
0
0
0
% K
% Leu:
0
10
50
0
0
0
0
0
0
10
0
0
10
0
0
% L
% Met:
0
20
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
10
0
0
0
70
10
0
20
10
0
0
20
0
0
% N
% Pro:
40
0
0
0
0
0
0
0
0
0
0
0
0
10
40
% P
% Gln:
0
0
0
0
10
0
20
10
0
0
0
0
0
0
0
% Q
% Arg:
20
0
0
50
0
0
0
0
0
50
40
0
0
0
0
% R
% Ser:
0
0
0
0
20
0
0
20
0
0
0
0
60
0
0
% S
% Thr:
20
0
0
20
0
10
30
60
0
0
0
0
0
0
20
% T
% Val:
0
0
10
10
10
0
10
0
0
0
0
10
0
20
0
% V
% Trp:
0
0
0
0
60
0
0
0
0
0
0
20
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
50
0
0
60
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _