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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERN2
All Species:
8.48
Human Site:
T465
Identified Species:
20.74
UniProt:
Q76MJ5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q76MJ5
NP_150296.3
926
102466
T465
V
V
E
K
Q
Q
E
T
P
L
A
P
A
D
F
Chimpanzee
Pan troglodytes
XP_510880
974
107065
T513
V
V
E
K
Q
Q
E
T
P
L
A
S
A
D
S
Rhesus Macaque
Macaca mulatta
XP_001089227
820
89327
H418
H
E
L
P
P
V
L
H
T
T
M
L
R
V
H
Dog
Lupus familis
XP_547090
925
102471
P463
E
K
Q
H
P
Q
Q
P
L
L
A
P
A
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2E3
911
101337
S453
L
M
R
Q
Q
Q
Q
S
P
S
A
P
A
G
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505283
1129
123221
A473
Q
R
L
E
Q
K
L
A
P
A
P
H
S
S
H
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392044
968
110555
S479
F
Q
Q
L
S
Q
G
S
R
E
N
N
S
T
S
Nematode Worm
Caenorhab. elegans
Q09499
967
109804
Q463
Q
C
G
R
Q
W
D
Q
Q
K
S
T
S
R
M
Sea Urchin
Strong. purpuratus
XP_786178
1112
123199
K535
V
F
K
A
L
I
L
K
G
I
S
R
Q
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32361
1115
126957
L619
G
A
V
N
D
G
S
L
K
S
E
K
D
N
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.2
77.6
84.2
N.A.
80.5
N.A.
N.A.
53.5
N.A.
N.A.
N.A.
N.A.
N.A.
38.4
37.4
36
Protein Similarity:
100
94.4
79.5
88.9
N.A.
86.2
N.A.
N.A.
61.8
N.A.
N.A.
N.A.
N.A.
N.A.
54.3
54.5
48.2
P-Site Identity:
100
86.6
0
40
N.A.
40
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
6.6
6.6
P-Site Similarity:
100
86.6
0
53.3
N.A.
73.3
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
33.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
10
0
10
40
0
40
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
10
0
0
0
0
0
10
30
10
% D
% Glu:
10
10
20
10
0
0
20
0
0
10
10
0
0
0
0
% E
% Phe:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
10
0
10
0
0
10
10
0
10
0
0
0
0
10
0
% G
% His:
10
0
0
10
0
0
0
10
0
0
0
10
0
0
20
% H
% Ile:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
10
10
20
0
10
0
10
10
10
0
10
0
10
0
% K
% Leu:
10
0
20
10
10
0
30
10
10
30
0
10
0
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
10
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
10
10
0
10
0
% N
% Pro:
0
0
0
10
20
0
0
10
40
0
10
30
0
0
30
% P
% Gln:
20
10
20
10
50
50
20
10
10
0
0
0
10
0
0
% Q
% Arg:
0
10
10
10
0
0
0
0
10
0
0
10
10
10
0
% R
% Ser:
0
0
0
0
10
0
10
20
0
20
20
10
30
10
20
% S
% Thr:
0
0
0
0
0
0
0
20
10
10
0
10
0
10
0
% T
% Val:
30
20
10
0
0
10
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _