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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERN2 All Species: 24.55
Human Site: Y860 Identified Species: 60
UniProt: Q76MJ5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q76MJ5 NP_150296.3 926 102466 Y860 V R N K K H H Y R E L P V E V
Chimpanzee Pan troglodytes XP_510880 974 107065 Y908 V R N K K H H Y R E L P V E V
Rhesus Macaque Macaca mulatta XP_001089227 820 89327 P761 S M A A A S F P Q S R I L S E
Dog Lupus familis XP_547090 925 102471 Y859 M R N K K H H Y R E L P T E V
Cat Felis silvestris
Mouse Mus musculus Q9Z2E3 911 101337 Y847 M R N K K H H Y R E L P A E V
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505283 1129 123221 Y868 M R N K K H H Y H E L P G E A
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392044 968 110555 Y852 L R N K K H H Y R E L S Q Q A
Nematode Worm Caenorhab. elegans Q09499 967 109804 Y857 M R N K K H H Y R E L P E D V
Sea Urchin Strong. purpuratus XP_786178 1112 123199 F927 M R N K K H H F R E L P E E V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32361 1115 126957 L1048 R K Y H S S K L M D L L R A L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.2 77.6 84.2 N.A. 80.5 N.A. N.A. 53.5 N.A. N.A. N.A. N.A. N.A. 38.4 37.4 36
Protein Similarity: 100 94.4 79.5 88.9 N.A. 86.2 N.A. N.A. 61.8 N.A. N.A. N.A. N.A. N.A. 54.3 54.5 48.2
P-Site Identity: 100 100 0 86.6 N.A. 86.6 N.A. N.A. 73.3 N.A. N.A. N.A. N.A. N.A. 66.6 80 80
P-Site Similarity: 100 100 13.3 93.3 N.A. 93.3 N.A. N.A. 80 N.A. N.A. N.A. N.A. N.A. 80 93.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 10 0 0 0 0 0 0 0 10 10 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 80 0 0 20 60 10 % E
% Phe: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 10 0 80 80 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 10 0 80 80 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 0 0 10 0 0 90 10 10 0 10 % L
% Met: 50 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 80 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 0 0 70 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 10 10 0 % Q
% Arg: 10 80 0 0 0 0 0 0 70 0 10 0 10 0 0 % R
% Ser: 10 0 0 0 10 20 0 0 0 10 0 10 0 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % T
% Val: 20 0 0 0 0 0 0 0 0 0 0 0 20 0 60 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 70 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _