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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECW1
All Species:
29.39
Human Site:
S1293
Identified Species:
53.89
UniProt:
Q76N89
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q76N89
NP_055867.3
1606
179554
S1293
G
E
E
G
L
D
Y
S
G
P
S
R
E
F
F
Chimpanzee
Pan troglodytes
XP_516001
1572
175733
S1259
G
E
E
G
L
D
Y
S
G
P
S
R
E
F
F
Rhesus Macaque
Macaca mulatta
XP_001096775
1606
179529
S1293
G
E
E
G
L
D
Y
S
G
P
S
R
E
F
F
Dog
Lupus familis
XP_850781
1366
151109
Y1071
S
Q
E
L
F
N
P
Y
Y
G
L
F
E
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4P8
1604
179451
S1291
G
E
E
G
L
D
Y
S
G
P
S
R
E
F
F
Rat
Rattus norvegicus
Q62940
887
102376
G592
E
M
F
N
P
Y
Y
G
L
F
E
Y
S
A
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507682
1657
184662
S1344
G
E
E
G
L
D
Y
S
G
P
S
R
E
F
F
Chicken
Gallus gallus
XP_418870
1586
179204
S1273
G
E
E
G
L
D
Y
S
G
P
S
R
E
F
F
Frog
Xenopus laevis
Q2TAS2
751
86306
Y456
S
H
D
M
L
N
P
Y
Y
G
L
F
Q
Y
S
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
Y470
S
H
E
M
L
N
P
Y
Y
G
L
F
Q
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
Y712
K
E
M
F
N
P
Y
Y
G
L
F
E
Y
S
A
Honey Bee
Apis mellifera
XP_392900
1204
136801
Y908
S
R
E
L
F
N
P
Y
Y
G
L
F
E
Y
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
P514
L
S
H
E
M
F
N
P
F
Y
C
L
F
E
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56
99.1
75.2
N.A.
88.2
24.9
N.A.
82.1
80.3
23.1
23.4
N.A.
25.1
39
N.A.
N.A.
Protein Similarity:
100
67.8
99.6
78.6
N.A.
92.2
37.8
N.A.
86.9
86.8
33.2
33.6
N.A.
39.4
52.4
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
100
6.6
N.A.
100
100
6.6
13.3
N.A.
20
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
100
6.6
N.A.
100
100
33.3
33.3
N.A.
20
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
8
0
0
47
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
54
70
8
0
0
0
0
0
0
8
8
62
8
0
% E
% Phe:
0
0
8
8
16
8
0
0
8
8
8
31
8
47
47
% F
% Gly:
47
0
0
47
0
0
0
8
54
31
0
0
0
0
0
% G
% His:
0
16
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
16
62
0
0
0
8
8
31
8
0
0
0
% L
% Met:
0
8
8
16
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
31
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
8
31
8
0
47
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
16
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
47
0
0
0
% R
% Ser:
31
8
0
0
0
0
0
47
0
0
47
0
8
8
31
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
62
39
31
8
0
8
8
31
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _