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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECW1
All Species:
4.55
Human Site:
S937
Identified Species:
8.33
UniProt:
Q76N89
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q76N89
NP_055867.3
1606
179554
S937
L
D
L
R
R
E
G
S
L
S
P
V
N
S
Q
Chimpanzee
Pan troglodytes
XP_516001
1572
175733
L915
T
S
R
S
R
L
T
L
L
L
Q
S
P
P
V
Rhesus Macaque
Macaca mulatta
XP_001096775
1606
179529
S937
L
D
L
R
R
E
G
S
L
S
P
V
N
S
Q
Dog
Lupus familis
XP_850781
1366
151109
K744
F
T
S
S
T
C
L
K
H
M
I
L
K
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4P8
1604
179451
G934
S
L
D
L
R
R
E
G
S
L
S
P
V
N
S
Rat
Rattus norvegicus
Q62940
887
102376
V265
V
L
G
R
T
Y
Y
V
N
H
E
S
R
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507682
1657
184662
R985
Q
P
N
L
E
L
R
R
E
G
S
L
S
P
V
Chicken
Gallus gallus
XP_418870
1586
179204
P920
R
R
E
G
S
L
S
P
V
N
S
Q
K
I
T
Frog
Xenopus laevis
Q2TAS2
751
86306
R129
P
N
D
N
D
T
V
R
G
Q
I
V
V
S
L
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
G143
L
Q
S
R
D
R
I
G
S
G
G
P
V
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
V385
Y
N
S
L
R
H
P
V
A
H
R
Q
P
E
I
Honey Bee
Apis mellifera
XP_392900
1204
136801
P581
I
E
R
N
E
T
E
P
F
D
I
S
T
S
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
Q187
H
P
S
R
G
T
A
Q
A
V
E
S
T
L
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56
99.1
75.2
N.A.
88.2
24.9
N.A.
82.1
80.3
23.1
23.4
N.A.
25.1
39
N.A.
N.A.
Protein Similarity:
100
67.8
99.6
78.6
N.A.
92.2
37.8
N.A.
86.9
86.8
33.2
33.6
N.A.
39.4
52.4
N.A.
N.A.
P-Site Identity:
100
13.3
100
0
N.A.
6.6
6.6
N.A.
0
0
13.3
13.3
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
13.3
100
13.3
N.A.
13.3
20
N.A.
13.3
13.3
20
13.3
N.A.
13.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
16
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
16
0
16
0
0
0
0
8
0
0
0
0
8
% D
% Glu:
0
8
8
0
16
16
16
0
8
0
16
0
0
8
0
% E
% Phe:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
8
0
16
16
8
16
8
0
0
0
0
% G
% His:
8
0
0
0
0
8
0
0
8
16
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
8
0
0
0
24
0
0
8
8
% I
% Lys:
0
0
0
0
0
0
0
8
0
0
0
0
16
0
0
% K
% Leu:
24
16
16
24
0
24
8
8
24
16
0
16
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
16
8
16
0
0
0
0
8
8
0
0
16
8
0
% N
% Pro:
8
16
0
0
0
0
8
16
0
0
16
16
16
16
8
% P
% Gln:
8
8
0
0
0
0
0
8
0
8
8
16
0
0
24
% Q
% Arg:
8
8
16
39
39
16
8
16
0
0
8
0
8
0
8
% R
% Ser:
8
8
31
16
8
0
8
16
16
16
24
31
8
31
8
% S
% Thr:
8
8
0
0
16
24
8
0
0
0
0
0
16
8
16
% T
% Val:
8
0
0
0
0
0
8
16
8
8
0
24
24
16
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _