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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HECW1
All Species:
13.64
Human Site:
Y321
Identified Species:
25
UniProt:
Q76N89
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q76N89
NP_055867.3
1606
179554
Y321
I
G
D
R
V
V
S
Y
T
L
G
R
R
L
P
Chimpanzee
Pan troglodytes
XP_516001
1572
175733
R305
M
L
S
Y
N
L
G
R
R
L
P
A
D
H
V
Rhesus Macaque
Macaca mulatta
XP_001096775
1606
179529
Y321
I
G
D
R
V
V
S
Y
T
L
G
R
R
L
P
Dog
Lupus familis
XP_850781
1366
151109
P138
D
K
F
A
K
S
R
P
I
I
K
R
F
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K4P8
1604
179451
Y321
I
G
D
R
V
V
S
Y
T
L
G
R
R
L
P
Rat
Rattus norvegicus
Q62940
887
102376
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507682
1657
184662
Y367
I
G
D
R
V
V
S
Y
T
L
G
R
R
L
P
Chicken
Gallus gallus
XP_418870
1586
179204
G313
L
P
T
D
H
V
S
G
Q
L
Q
F
R
F
E
Frog
Xenopus laevis
Q2TAS2
751
86306
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVI3
1007
114856
Honey Bee
Apis mellifera
XP_392900
1204
136801
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56
99.1
75.2
N.A.
88.2
24.9
N.A.
82.1
80.3
23.1
23.4
N.A.
25.1
39
N.A.
N.A.
Protein Similarity:
100
67.8
99.6
78.6
N.A.
92.2
37.8
N.A.
86.9
86.8
33.2
33.6
N.A.
39.4
52.4
N.A.
N.A.
P-Site Identity:
100
6.6
100
13.3
N.A.
100
0
N.A.
100
26.6
0
0
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
20
100
20
N.A.
100
0
N.A.
100
33.3
0
0
N.A.
0
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
36.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
31
8
0
0
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
8
8
8
0
% F
% Gly:
0
31
0
0
0
0
8
8
0
0
31
0
0
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
31
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% I
% Lys:
0
8
0
0
8
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
8
8
0
0
0
8
0
0
0
47
0
0
0
39
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
8
0
0
8
0
0
0
31
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% Q
% Arg:
0
0
0
31
0
0
8
8
8
0
0
39
39
0
0
% R
% Ser:
0
0
8
0
0
8
39
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
31
0
0
0
0
0
0
% T
% Val:
0
0
0
0
31
39
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
31
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _