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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK2
All Species:
10.61
Human Site:
S26
Identified Species:
19.44
UniProt:
Q7KZI7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7KZI7
NP_001034558.2
788
87911
S26
P
T
L
G
H
L
D
S
K
P
S
S
K
S
N
Chimpanzee
Pan troglodytes
XP_001172839
796
89049
K33
E
P
L
I
Q
P
T
K
S
S
S
R
Q
N
I
Rhesus Macaque
Macaca mulatta
XP_001115591
788
87964
S26
P
T
L
G
H
L
D
S
K
P
S
S
K
S
N
Dog
Lupus familis
XP_540890
798
88683
P46
P
T
L
G
H
L
D
P
K
P
T
S
K
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q05512
776
86287
S26
P
T
L
G
H
L
D
S
K
P
S
S
K
S
N
Rat
Rattus norvegicus
O08679
722
80853
H23
T
E
Q
P
T
L
G
H
L
D
S
K
P
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511751
793
88836
T32
T
E
P
H
I
Q
P
T
K
S
S
R
Q
N
V
Chicken
Gallus gallus
Q9IA88
798
88848
I28
L
R
V
G
F
Y
D
I
E
R
T
L
G
K
G
Frog
Xenopus laevis
NP_001080425
785
87931
G30
A
D
Q
K
T
S
S
G
G
S
S
K
P
N
M
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
P32
Q
Q
Q
Q
Q
Q
Q
P
A
S
A
A
L
H
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
H143
T
S
G
S
S
S
S
H
A
R
S
T
G
Q
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.2
99.7
95.1
N.A.
96.6
89.9
N.A.
68.4
30.3
84.3
27.5
N.A.
N.A.
N.A.
38.8
N.A.
Protein Similarity:
100
80.4
99.7
96.2
N.A.
97.7
90.9
N.A.
80.5
48.7
91.7
42.7
N.A.
N.A.
N.A.
49.9
N.A.
P-Site Identity:
100
13.3
100
86.6
N.A.
100
20
N.A.
13.3
13.3
6.6
0
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
26.6
100
93.3
N.A.
100
26.6
N.A.
33.3
33.3
13.3
13.3
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.5
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.1
45.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
16
0
8
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
39
0
0
8
0
0
0
0
0
% D
% Glu:
8
16
0
0
0
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
39
0
0
8
8
8
0
0
0
16
0
8
% G
% His:
0
0
0
8
31
0
0
16
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
8
8
0
0
8
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
8
0
0
0
8
39
0
0
16
31
8
0
% K
% Leu:
8
0
39
0
0
39
0
0
8
0
0
8
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
24
31
% N
% Pro:
31
8
8
8
0
8
8
16
0
31
0
0
16
0
8
% P
% Gln:
8
8
24
8
16
16
8
0
0
0
0
0
16
8
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
16
0
16
0
0
0
% R
% Ser:
0
8
0
8
8
16
16
24
8
31
62
31
0
39
16
% S
% Thr:
24
31
0
0
16
0
8
8
0
0
16
8
0
0
0
% T
% Val:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _