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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK2
All Species:
6.06
Human Site:
S675
Identified Species:
11.11
UniProt:
Q7KZI7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7KZI7
NP_001034558.2
788
87911
S675
L
R
P
H
V
V
G
S
G
G
N
D
K
E
K
Chimpanzee
Pan troglodytes
XP_001172839
796
89049
P685
S
R
S
T
S
G
E
P
K
E
R
D
K
E
E
Rhesus Macaque
Macaca mulatta
XP_001115591
788
87964
S675
L
R
P
H
V
E
G
S
G
V
N
D
K
E
K
Dog
Lupus familis
XP_540890
798
88683
E694
G
N
D
K
E
K
E
E
F
R
E
A
K
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q05512
776
86287
E672
G
T
D
K
D
K
E
E
F
R
E
A
K
P
R
Rat
Rattus norvegicus
O08679
722
80853
R620
D
K
E
K
E
E
F
R
E
A
K
P
R
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511751
793
88836
P682
S
R
S
T
S
G
E
P
K
E
R
E
K
E
D
Chicken
Gallus gallus
Q9IA88
798
88848
T679
A
C
P
Q
T
S
Q
T
S
A
T
N
G
L
P
Frog
Xenopus laevis
NP_001080425
785
87931
K677
L
S
V
V
D
K
E
K
D
K
E
D
H
R
D
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
F835
H
S
R
S
L
S
R
F
H
T
S
A
Y
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
T1013
G
N
V
S
I
G
A
T
G
P
S
A
N
N
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
E409
H
P
R
E
I
M
N
E
V
L
K
A
L
Q
E
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
A531
I
A
L
K
N
L
G
A
E
W
A
K
P
S
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.2
99.7
95.1
N.A.
96.6
89.9
N.A.
68.4
30.3
84.3
27.5
N.A.
N.A.
N.A.
38.8
N.A.
Protein Similarity:
100
80.4
99.7
96.2
N.A.
97.7
90.9
N.A.
80.5
48.7
91.7
42.7
N.A.
N.A.
N.A.
49.9
N.A.
P-Site Identity:
100
26.6
86.6
6.6
N.A.
6.6
0
N.A.
20
6.6
13.3
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
33.3
86.6
13.3
N.A.
13.3
13.3
N.A.
26.6
20
13.3
26.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.5
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.1
45.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
8
8
0
16
8
39
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
16
0
16
0
0
0
8
0
0
31
0
0
16
% D
% Glu:
0
0
8
8
16
16
39
24
16
16
24
8
0
39
24
% E
% Phe:
0
0
0
0
0
0
8
8
16
0
0
0
0
0
0
% F
% Gly:
24
0
0
0
0
24
24
0
24
8
0
0
8
0
0
% G
% His:
16
0
0
16
0
0
0
0
8
0
0
0
8
0
0
% H
% Ile:
8
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
31
0
24
0
8
16
8
16
8
47
0
16
% K
% Leu:
24
0
8
0
8
8
0
0
0
8
0
0
8
8
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
16
0
0
8
0
8
0
0
0
16
8
8
8
0
% N
% Pro:
0
8
24
0
0
0
0
16
0
8
0
8
8
16
8
% P
% Gln:
0
0
0
8
0
0
8
0
0
0
0
0
0
8
8
% Q
% Arg:
0
31
16
0
0
0
8
8
0
16
16
0
8
8
16
% R
% Ser:
16
16
16
16
16
16
0
16
8
0
16
0
0
16
0
% S
% Thr:
0
8
0
16
8
0
0
16
0
8
8
0
0
0
0
% T
% Val:
0
0
16
8
16
8
0
0
8
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _