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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MARK2 All Species: 9.39
Human Site: T384 Identified Species: 17.22
UniProt: Q7KZI7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7KZI7 NP_001034558.2 788 87911 T384 P R P S A D L T N S S A P S P
Chimpanzee Pan troglodytes XP_001172839 796 89049 R391 G N L C Q R S R P S S D L N N
Rhesus Macaque Macaca mulatta XP_001115591 788 87964 T384 P R P S A D L T N S S A P S P
Dog Lupus familis XP_540890 798 88683 L403 K P R P S A D L T N S S A P S
Cat Felis silvestris
Mouse Mus musculus Q05512 776 86287 A381 T L K P R P S A D L T N S S A
Rat Rattus norvegicus O08679 722 80853 L331 K D P R R T E L M V S M G Y T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511751 793 88836 R390 G N L C L R S R P S S D L N N
Chicken Gallus gallus Q9IA88 798 88848 R385 S L T S E T L R S S L L Y Q Q
Frog Xenopus laevis NP_001080425 785 87931 S388 P R P P P D I S N S I V T S P
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 P479 P G F P R V A P Q A P F P P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 S501 T M A Q S L L S H S S I N V S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671 A120 G R L Q E D E A R N F F Q Q I
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 L242 V W S C G V I L Y V M L C R R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 68.2 99.7 95.1 N.A. 96.6 89.9 N.A. 68.4 30.3 84.3 27.5 N.A. N.A. N.A. 38.8 N.A.
Protein Similarity: 100 80.4 99.7 96.2 N.A. 97.7 90.9 N.A. 80.5 48.7 91.7 42.7 N.A. N.A. N.A. 49.9 N.A.
P-Site Identity: 100 13.3 100 6.6 N.A. 6.6 13.3 N.A. 13.3 20 53.3 13.3 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 100 20 100 26.6 N.A. 20 13.3 N.A. 20 26.6 66.6 20 N.A. N.A. N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 26.5 27.5 N.A.
Protein Similarity: N.A. N.A. N.A. 44.1 45.5 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 16 8 8 16 0 8 0 16 8 0 8 % A
% Cys: 0 0 0 24 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 8 0 0 0 31 8 0 8 0 0 16 0 0 0 % D
% Glu: 0 0 0 0 16 0 16 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 8 16 0 0 0 % F
% Gly: 24 8 0 0 8 0 0 0 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 16 0 0 0 8 8 0 0 8 % I
% Lys: 16 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 16 24 0 8 8 31 24 0 8 8 16 16 0 8 % L
% Met: 0 8 0 0 0 0 0 0 8 0 8 8 0 0 0 % M
% Asn: 0 16 0 0 0 0 0 0 24 16 0 8 8 16 16 % N
% Pro: 31 8 31 31 8 8 0 8 16 0 8 0 24 16 24 % P
% Gln: 0 0 0 16 8 0 0 0 8 0 0 0 8 16 8 % Q
% Arg: 0 31 8 8 24 16 0 24 8 0 0 0 0 8 8 % R
% Ser: 8 0 8 24 16 0 24 16 8 54 54 8 8 31 16 % S
% Thr: 16 0 8 0 0 16 0 16 8 0 8 0 8 0 8 % T
% Val: 8 0 0 0 0 16 0 0 0 16 0 8 0 8 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _