KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK2
All Species:
17.88
Human Site:
T467
Identified Species:
32.78
UniProt:
Q7KZI7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7KZI7
NP_001034558.2
788
87911
T467
G
L
E
R
K
K
T
T
P
T
P
S
T
N
S
Chimpanzee
Pan troglodytes
XP_001172839
796
89049
A474
G
S
K
S
E
M
T
A
S
P
L
V
G
P
E
Rhesus Macaque
Macaca mulatta
XP_001115591
788
87964
T467
G
L
E
R
K
K
T
T
P
T
P
S
T
N
S
Dog
Lupus familis
XP_540890
798
88683
T486
G
L
E
R
K
K
T
T
P
T
P
S
T
N
S
Cat
Felis silvestris
Mouse
Mus musculus
Q05512
776
86287
T464
G
L
D
R
K
K
T
T
P
A
P
S
T
N
S
Rat
Rattus norvegicus
O08679
722
80853
P414
R
S
S
D
Q
A
V
P
A
I
P
T
S
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511751
793
88836
V473
G
S
K
G
E
M
A
V
S
P
L
V
G
P
E
Chicken
Gallus gallus
Q9IA88
798
88848
S468
D
H
P
I
R
I
P
S
N
T
S
R
R
H
T
Frog
Xenopus laevis
NP_001080425
785
87931
P471
L
D
R
K
K
T
T
P
T
P
S
T
N
S
V
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
H562
S
P
L
V
T
S
P
H
P
I
P
A
V
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
S584
S
S
S
S
R
R
S
S
Q
N
D
A
A
A
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
S203
G
P
E
V
D
V
W
S
C
G
V
I
L
Y
A
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
E325
D
L
K
P
H
P
E
E
E
N
E
N
N
D
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.2
99.7
95.1
N.A.
96.6
89.9
N.A.
68.4
30.3
84.3
27.5
N.A.
N.A.
N.A.
38.8
N.A.
Protein Similarity:
100
80.4
99.7
96.2
N.A.
97.7
90.9
N.A.
80.5
48.7
91.7
42.7
N.A.
N.A.
N.A.
49.9
N.A.
P-Site Identity:
100
13.3
100
100
N.A.
86.6
20
N.A.
6.6
6.6
13.3
13.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
40
N.A.
20
33.3
33.3
20
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.5
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.1
45.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
8
8
8
0
16
8
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
16
8
8
8
8
0
0
0
0
0
8
0
0
8
0
% D
% Glu:
0
0
31
0
16
0
8
8
8
0
8
0
0
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
54
0
0
8
0
0
0
0
0
8
0
0
16
0
0
% G
% His:
0
8
0
0
8
0
0
8
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
8
0
8
0
0
0
16
0
8
0
0
0
% I
% Lys:
0
0
24
8
39
31
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
39
8
0
0
0
0
0
0
0
16
0
8
0
0
% L
% Met:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
16
0
8
16
39
0
% N
% Pro:
0
16
8
8
0
8
16
16
39
24
47
0
0
16
8
% P
% Gln:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
8
0
8
31
16
8
0
0
0
0
0
8
8
0
0
% R
% Ser:
16
31
16
16
0
8
8
24
16
0
16
31
8
8
47
% S
% Thr:
0
0
0
0
8
8
47
31
8
31
0
16
31
0
16
% T
% Val:
0
0
0
16
0
8
8
8
0
0
8
16
8
0
8
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _