Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: COX15 All Species: 12.42
Human Site: S44 Identified Species: 24.85
UniProt: Q7KZN9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7KZN9 NP_004367.2 410 46030 S44 P L R P G Q Y S T I S E V A L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534986 413 46123 S47 P L R P G Q Y S T I S E V A L
Cat Felis silvestris
Mouse Mus musculus Q8BJ03 413 45834 S47 P L R P G Q Y S T I T E V A L
Rat Rattus norvegicus NP_001028871 414 45896 G48 P L R P G Q Y G T I T E V A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001107598 383 42820 P25 S L V P L R Q P P R R G L P Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002664108 399 44592 G33 R Q W L L Q R G Q N T V S S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611855 393 44359 T28 L H Q T I A Q T A I K E I P V
Honey Bee Apis mellifera XP_394095 431 48942 H51 M K R N S I L H K D L F K G Y
Nematode Worm Caenorhab. elegans NP_496402 395 44952 Q26 S L L S Q G I Q N V R Q G F R
Sea Urchin Strong. purpuratus XP_780720 435 48261 L70 K P K V H M V L K P S R V Q T
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001131191 483 51816 N101 S T T A T A L N S T V A S G A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40086 486 54640 S61 S I R P F S L S S P V F K P H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 92 N.A. 89.8 88.6 N.A. N.A. 74.8 N.A. 71.2 N.A. 52.2 49.4 48.7 54
Protein Similarity: 100 N.A. N.A. 93.6 N.A. 93.4 93 N.A. N.A. 81.2 N.A. 81.4 N.A. 69 65.6 65.3 68
P-Site Identity: 100 N.A. N.A. 100 N.A. 93.3 86.6 N.A. N.A. 13.3 N.A. 6.6 N.A. 13.3 6.6 6.6 13.3
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 93.3 N.A. N.A. 26.6 N.A. 20 N.A. 40 6.6 20 20
Percent
Protein Identity: N.A. 41.4 N.A. N.A. 37.2 N.A.
Protein Similarity: N.A. 56.3 N.A. N.A. 51.2 N.A.
P-Site Identity: N.A. 0 N.A. N.A. 20 N.A.
P-Site Similarity: N.A. 13.3 N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 17 0 0 9 0 0 9 0 34 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 42 0 0 0 % E
% Phe: 0 0 0 0 9 0 0 0 0 0 0 17 0 9 0 % F
% Gly: 0 0 0 0 34 9 0 17 0 0 0 9 9 17 9 % G
% His: 0 9 0 0 9 0 0 9 0 0 0 0 0 0 9 % H
% Ile: 0 9 0 0 9 9 9 0 0 42 0 0 9 0 0 % I
% Lys: 9 9 9 0 0 0 0 0 17 0 9 0 17 0 0 % K
% Leu: 9 50 9 9 17 0 25 9 0 0 9 0 9 0 34 % L
% Met: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 9 9 9 0 0 0 0 0 % N
% Pro: 34 9 0 50 0 0 0 9 9 17 0 0 0 25 0 % P
% Gln: 0 9 9 0 9 42 17 9 9 0 0 9 0 9 9 % Q
% Arg: 9 0 50 0 0 9 9 0 0 9 17 9 0 0 9 % R
% Ser: 34 0 0 9 9 9 0 34 17 0 25 0 17 9 0 % S
% Thr: 0 9 9 9 9 0 0 9 34 9 25 0 0 0 9 % T
% Val: 0 0 9 9 0 0 9 0 0 9 17 9 42 0 9 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 34 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _