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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COX15
All Species:
19.7
Human Site:
T254
Identified Species:
39.39
UniProt:
Q7KZN9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7KZN9
NP_004367.2
410
46030
T254
P
P
H
K
L
P
E
T
H
Q
L
L
Q
L
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534986
413
46123
T257
S
Q
H
K
L
P
E
T
R
Q
L
L
W
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BJ03
413
45834
T257
P
Q
H
K
L
P
E
T
R
Q
L
L
W
L
R
Rat
Rattus norvegicus
NP_001028871
414
45896
T258
P
Q
H
K
I
P
E
T
R
Q
L
L
W
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001107598
383
42820
T227
P
R
H
Q
L
H
E
T
R
Q
L
L
Q
L
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002664108
399
44592
S243
P
A
N
R
M
P
D
S
R
Q
L
L
N
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611855
393
44359
A234
T
N
T
F
V
I
Q
A
K
K
A
F
N
I
K
Honey Bee
Apis mellifera
XP_394095
431
48942
K272
N
V
N
I
S
D
L
K
S
K
L
K
K
F
R
Nematode Worm
Caenorhab. elegans
NP_496402
395
44952
R239
P
H
D
L
S
K
V
R
S
K
L
G
A
L
R
Sea Urchin
Strong. purpuratus
XP_780720
435
48261
S279
K
P
L
T
I
A
N
S
K
N
L
S
L
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001131191
483
51816
V314
P
T
G
S
M
S
W
V
N
G
A
A
K
I
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40086
486
54640
N285
S
L
F
K
K
L
D
N
P
A
I
G
P
M
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
92
N.A.
89.8
88.6
N.A.
N.A.
74.8
N.A.
71.2
N.A.
52.2
49.4
48.7
54
Protein Similarity:
100
N.A.
N.A.
93.6
N.A.
93.4
93
N.A.
N.A.
81.2
N.A.
81.4
N.A.
69
65.6
65.3
68
P-Site Identity:
100
N.A.
N.A.
73.3
N.A.
80
73.3
N.A.
N.A.
73.3
N.A.
46.6
N.A.
0
13.3
26.6
26.6
P-Site Similarity:
100
N.A.
N.A.
73.3
N.A.
80
80
N.A.
N.A.
80
N.A.
80
N.A.
33.3
33.3
33.3
40
Percent
Protein Identity:
N.A.
41.4
N.A.
N.A.
37.2
N.A.
Protein Similarity:
N.A.
56.3
N.A.
N.A.
51.2
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
40
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
0
9
0
9
17
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
9
17
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
42
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
9
9
0
0
0
0
0
0
0
9
0
9
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
9
0
17
0
0
0
% G
% His:
0
9
42
0
0
9
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
17
9
0
0
0
0
9
0
0
17
0
% I
% Lys:
9
0
0
42
9
9
0
9
17
25
0
9
17
0
9
% K
% Leu:
0
9
9
9
34
9
9
0
0
0
75
50
9
67
0
% L
% Met:
0
0
0
0
17
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
9
9
17
0
0
0
9
9
9
9
0
0
17
0
0
% N
% Pro:
59
17
0
0
0
42
0
0
9
0
0
0
9
0
0
% P
% Gln:
0
25
0
9
0
0
9
0
0
50
0
0
17
0
0
% Q
% Arg:
0
9
0
9
0
0
0
9
42
0
0
0
0
0
92
% R
% Ser:
17
0
0
9
17
9
0
17
17
0
0
9
0
0
0
% S
% Thr:
9
9
9
9
0
0
0
42
0
0
0
0
0
0
0
% T
% Val:
0
9
0
0
9
0
9
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
25
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _