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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX46
All Species:
26.36
Human Site:
S106
Identified Species:
36.25
UniProt:
Q7L014
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L014
NP_055644.2
1031
117362
S106
G
R
R
S
R
S
S
S
P
G
N
K
S
K
K
Chimpanzee
Pan troglodytes
XP_517939
1173
133261
S248
G
R
R
S
R
S
S
S
P
G
N
K
S
K
K
Rhesus Macaque
Macaca mulatta
XP_001109331
1031
117356
S106
G
R
R
S
R
S
S
S
P
G
N
K
S
K
K
Dog
Lupus familis
XP_531911
1031
117344
S106
G
R
R
S
R
S
S
S
P
G
N
K
S
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q569Z5
1032
117430
S106
G
R
R
S
R
S
S
S
P
G
S
K
T
K
K
Rat
Rattus norvegicus
Q62780
1032
117367
S106
G
R
R
S
R
S
S
S
P
G
S
K
S
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510706
974
110456
K107
E
E
E
M
R
K
R
K
E
R
V
E
K
W
R
Chicken
Gallus gallus
Q5F485
944
103035
S106
R
Q
Q
F
N
S
K
S
A
D
S
D
S
D
D
Frog
Xenopus laevis
Q7ZY47
947
104061
S107
R
S
K
T
D
S
D
S
E
E
D
P
L
E
A
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
K106
T
A
D
K
K
K
I
K
E
E
K
E
E
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573020
1224
136263
R143
E
R
E
R
D
K
D
R
E
R
D
R
Q
R
E
Honey Bee
Apis mellifera
XP_001122722
1018
114528
K109
R
S
R
S
R
E
R
K
E
K
E
K
G
D
S
Nematode Worm
Caenorhab. elegans
NP_001033411
970
109887
N108
G
V
E
R
R
R
R
N
V
E
K
W
R
A
Q
Sea Urchin
Strong. purpuratus
XP_784902
869
99209
D78
R
S
R
S
R
D
R
D
R
R
R
S
P
P
R
Poplar Tree
Populus trichocarpa
XP_002301895
1112
128539
E132
D
R
D
K
D
R
E
E
K
R
E
R
A
K
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0U8
1166
133015
E120
K
R
R
V
N
E
K
E
R
G
H
R
E
H
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
D116
R
D
R
S
R
D
P
D
R
E
Y
R
P
R
R
Conservation
Percent
Protein Identity:
100
87.8
99.9
99.8
N.A.
98.8
98.6
N.A.
89.6
29.7
30.2
83
N.A.
49.6
63.8
47.8
54.5
Protein Similarity:
100
87.8
99.9
99.8
N.A.
99.5
99.3
N.A.
92.5
45.7
48.2
90.1
N.A.
62.9
75.9
65.9
65.8
P-Site Identity:
100
100
100
100
N.A.
86.6
93.3
N.A.
6.6
20
13.3
6.6
N.A.
6.6
26.6
13.3
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
40
40
26.6
N.A.
33.3
26.6
26.6
26.6
Percent
Protein Identity:
43.9
N.A.
N.A.
43.3
N.A.
41.3
Protein Similarity:
60.1
N.A.
N.A.
58.5
N.A.
56.2
P-Site Identity:
13.3
N.A.
N.A.
20
N.A.
20
P-Site Similarity:
33.3
N.A.
N.A.
40
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
0
0
0
0
0
6
0
0
0
6
6
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
6
12
0
18
12
12
12
0
6
12
6
0
12
6
% D
% Glu:
12
6
18
0
0
12
6
12
30
24
12
12
12
12
18
% E
% Phe:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
42
0
0
0
0
0
0
0
0
42
0
0
6
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
6
0
0
6
0
% H
% Ile:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% I
% Lys:
6
0
6
12
6
18
12
18
6
6
12
42
6
42
42
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% L
% Met:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
6
0
0
24
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
6
0
36
0
0
6
12
6
0
% P
% Gln:
0
6
6
0
0
0
0
0
0
0
0
0
6
0
6
% Q
% Arg:
30
53
59
12
65
12
24
6
18
24
6
24
6
12
18
% R
% Ser:
0
18
0
53
0
48
36
48
0
0
18
6
36
0
6
% S
% Thr:
6
0
0
6
0
0
0
0
0
0
0
0
6
0
0
% T
% Val:
0
6
0
6
0
0
0
0
6
0
6
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
6
0
6
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _