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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX46
All Species:
31.52
Human Site:
S12
Identified Species:
43.33
UniProt:
Q7L014
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L014
NP_055644.2
1031
117362
S12
S
R
H
Y
R
K
R
S
A
S
R
G
R
S
G
Chimpanzee
Pan troglodytes
XP_517939
1173
133261
S154
S
R
H
Y
R
K
R
S
A
S
R
G
R
S
G
Rhesus Macaque
Macaca mulatta
XP_001109331
1031
117356
S12
S
R
H
Y
R
K
R
S
A
S
R
G
R
S
G
Dog
Lupus familis
XP_531911
1031
117344
S12
S
R
H
Y
R
K
R
S
A
S
R
G
R
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q569Z5
1032
117430
S12
S
R
H
Y
R
K
R
S
A
S
R
G
R
S
G
Rat
Rattus norvegicus
Q62780
1032
117367
S12
S
R
H
Y
R
K
R
S
A
S
R
G
R
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510706
974
110456
R13
S
R
D
R
K
R
P
R
R
S
R
S
R
E
R
Chicken
Gallus gallus
Q5F485
944
103035
R12
K
G
G
P
G
T
K
R
G
F
G
F
G
G
F
Frog
Xenopus laevis
Q7ZY47
947
104061
G13
G
G
S
G
N
K
R
G
F
G
F
G
G
F
A
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
S12
S
R
H
Y
R
K
R
S
S
S
R
G
R
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573020
1224
136263
S49
R
D
Y
D
M
G
K
S
R
N
G
G
G
G
G
Honey Bee
Apis mellifera
XP_001122722
1018
114528
H15
L
L
G
R
D
R
H
H
R
R
R
S
R
S
R
Nematode Worm
Caenorhab. elegans
NP_001033411
970
109887
S14
K
E
H
K
R
K
R
S
R
S
K
E
R
K
R
Sea Urchin
Strong. purpuratus
XP_784902
869
99209
Poplar Tree
Populus trichocarpa
XP_002301895
1112
128539
D38
R
D
R
D
R
D
R
D
R
N
G
E
R
H
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0U8
1166
133015
R26
E
A
D
L
K
K
S
R
R
D
R
D
R
S
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
K22
S
L
S
A
R
K
R
K
D
D
D
R
R
D
R
Conservation
Percent
Protein Identity:
100
87.8
99.9
99.8
N.A.
98.8
98.6
N.A.
89.6
29.7
30.2
83
N.A.
49.6
63.8
47.8
54.5
Protein Similarity:
100
87.8
99.9
99.8
N.A.
99.5
99.3
N.A.
92.5
45.7
48.2
90.1
N.A.
62.9
75.9
65.9
65.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
33.3
0
20
93.3
N.A.
20
20
46.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
46.6
6.6
20
100
N.A.
40
26.6
53.3
0
Percent
Protein Identity:
43.9
N.A.
N.A.
43.3
N.A.
41.3
Protein Similarity:
60.1
N.A.
N.A.
58.5
N.A.
56.2
P-Site Identity:
20
N.A.
N.A.
26.6
N.A.
33.3
P-Site Similarity:
26.6
N.A.
N.A.
33.3
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
6
0
0
0
0
36
0
0
0
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
12
12
6
6
0
6
6
12
6
6
0
6
0
% D
% Glu:
6
6
0
0
0
0
0
0
0
0
0
12
0
6
0
% E
% Phe:
0
0
0
0
0
0
0
0
6
6
6
6
0
6
6
% F
% Gly:
6
12
12
6
6
6
0
6
6
6
18
53
18
12
48
% G
% His:
0
0
48
0
0
0
6
6
0
0
0
0
0
6
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
6
12
65
12
6
0
0
6
0
0
6
0
% K
% Leu:
6
12
0
6
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
6
0
0
0
0
12
0
0
0
0
6
% N
% Pro:
0
0
0
6
0
0
6
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
48
6
12
59
12
65
18
36
6
59
6
77
0
30
% R
% Ser:
53
0
12
0
0
0
6
53
6
53
0
12
0
53
0
% S
% Thr:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
6
42
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _