KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX46
All Species:
26.97
Human Site:
S130
Identified Species:
37.08
UniProt:
Q7L014
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L014
NP_055644.2
1031
117362
S130
K
T
D
G
G
E
S
S
K
E
K
K
K
D
K
Chimpanzee
Pan troglodytes
XP_517939
1173
133261
S272
K
T
D
G
G
E
S
S
K
E
K
K
K
D
K
Rhesus Macaque
Macaca mulatta
XP_001109331
1031
117356
S130
K
T
D
G
G
E
S
S
K
E
K
K
K
D
K
Dog
Lupus familis
XP_531911
1031
117344
S130
K
T
D
S
G
E
S
S
K
E
K
K
K
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q569Z5
1032
117430
S130
K
A
E
G
G
D
S
S
K
E
K
K
K
D
K
Rat
Rattus norvegicus
Q62780
1032
117367
S130
K
A
E
G
G
D
S
S
K
E
K
K
K
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510706
974
110456
E131
N
I
G
E
L
K
K
E
I
E
E
M
K
Q
G
Chicken
Gallus gallus
Q5F485
944
103035
D130
V
E
D
Q
A
A
R
D
M
K
R
L
E
D
K
Frog
Xenopus laevis
Q7ZY47
947
104061
E131
A
K
D
M
R
K
L
E
E
R
D
K
E
K
A
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
K130
T
L
E
E
E
M
R
K
R
K
E
R
V
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573020
1224
136263
P167
A
A
A
P
L
I
I
P
L
L
S
T
S
C
S
Honey Bee
Apis mellifera
XP_001122722
1018
114528
L133
L
D
K
K
R
L
E
L
E
M
Q
K
R
R
E
Nematode Worm
Caenorhab. elegans
NP_001033411
970
109887
S132
S
E
Q
S
D
E
K
S
E
K
K
P
W
N
L
Sea Urchin
Strong. purpuratus
XP_784902
869
99209
S102
V
R
E
R
D
R
R
S
R
R
S
R
S
R
S
Poplar Tree
Populus trichocarpa
XP_002301895
1112
128539
E156
E
R
E
R
E
K
R
E
R
E
R
E
R
D
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0U8
1166
133015
K144
D
R
E
R
E
E
R
K
D
K
E
R
E
R
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
S140
R
R
E
G
T
A
E
S
S
S
H
R
R
D
D
Conservation
Percent
Protein Identity:
100
87.8
99.9
99.8
N.A.
98.8
98.6
N.A.
89.6
29.7
30.2
83
N.A.
49.6
63.8
47.8
54.5
Protein Similarity:
100
87.8
99.9
99.8
N.A.
99.5
99.3
N.A.
92.5
45.7
48.2
90.1
N.A.
62.9
75.9
65.9
65.8
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
13.3
20
13.3
6.6
N.A.
0
6.6
20
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
26.6
40
33.3
46.6
N.A.
0
33.3
40
26.6
Percent
Protein Identity:
43.9
N.A.
N.A.
43.3
N.A.
41.3
Protein Similarity:
60.1
N.A.
N.A.
58.5
N.A.
56.2
P-Site Identity:
13.3
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
66.6
N.A.
N.A.
46.6
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
18
6
0
6
12
0
0
0
0
0
0
0
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% C
% Asp:
6
6
36
0
12
12
0
6
6
0
6
0
0
53
6
% D
% Glu:
6
12
42
12
18
36
12
18
18
48
18
6
18
6
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
6
36
36
0
0
0
0
0
0
0
0
0
6
% G
% His:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% H
% Ile:
0
6
0
0
0
6
6
0
6
0
0
0
0
0
0
% I
% Lys:
36
6
6
6
0
18
12
12
36
24
42
48
42
6
48
% K
% Leu:
6
6
0
0
12
6
6
6
6
6
0
6
0
0
6
% L
% Met:
0
0
0
6
0
6
0
0
6
6
0
6
0
0
0
% M
% Asn:
6
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% N
% Pro:
0
0
0
6
0
0
0
6
0
0
0
6
0
0
0
% P
% Gln:
0
0
6
6
0
0
0
0
0
0
6
0
0
6
0
% Q
% Arg:
6
24
0
18
12
6
30
0
18
12
12
24
18
18
6
% R
% Ser:
6
0
0
12
0
0
36
53
6
6
12
0
12
0
12
% S
% Thr:
6
24
0
0
6
0
0
0
0
0
0
6
0
0
0
% T
% Val:
12
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _