Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX46 All Species: 23.03
Human Site: S277 Identified Species: 31.67
UniProt: Q7L014 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L014 NP_055644.2 1031 117362 S277 T K K A V V D S D K K K G E L
Chimpanzee Pan troglodytes XP_517939 1173 133261 S419 T K K A V V D S D K K K G E L
Rhesus Macaque Macaca mulatta XP_001109331 1031 117356 S277 T K K A V V D S D K K K G E L
Dog Lupus familis XP_531911 1031 117344 S277 T K K A V V D S D K K K G E L
Cat Felis silvestris
Mouse Mus musculus Q569Z5 1032 117430 A277 T K K A V V D A D K K K G E L
Rat Rattus norvegicus Q62780 1032 117367 A277 T K K A V V D A D K K K G E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510706 974 110456 S220 T K K A T V E S E K K K G E L
Chicken Gallus gallus Q5F485 944 103035 S206 P L P P I D H S E I E Y P P F
Frog Xenopus laevis Q7ZY47 947 104061 F210 T E I E Y P P F E K N F Y E E
Zebra Danio Brachydanio rerio Q4TVV3 1018 115121 T246 T K K M P H A T K K K G E L M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573020 1224 136263 T415 G V A K K K T T T L K K G E V
Honey Bee Apis mellifera XP_001122722 1018 114528 K260 V T G V A K K K V Q K Q K G E
Nematode Worm Caenorhab. elegans NP_001033411 970 109887 K212 V T I V Q E E K P E P E K G Q
Sea Urchin Strong. purpuratus XP_784902 869 99209 V178 E K E E T K E V K E E K G L E
Poplar Tree Populus trichocarpa XP_002301895 1112 128539 D315 L E E N A K P D E E E I D P L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8H0U8 1166 133015 K334 E E G H P E E K S E T E M D V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SH33 1194 131283 E410 Q K E S M A M E I D S A P S N
Conservation
Percent
Protein Identity: 100 87.8 99.9 99.8 N.A. 98.8 98.6 N.A. 89.6 29.7 30.2 83 N.A. 49.6 63.8 47.8 54.5
Protein Similarity: 100 87.8 99.9 99.8 N.A. 99.5 99.3 N.A. 92.5 45.7 48.2 90.1 N.A. 62.9 75.9 65.9 65.8
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 80 6.6 20 33.3 N.A. 26.6 6.6 0 20
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 26.6 33.3 46.6 N.A. 40 20 20 46.6
Percent
Protein Identity: 43.9 N.A. N.A. 43.3 N.A. 41.3
Protein Similarity: 60.1 N.A. N.A. 58.5 N.A. 56.2
P-Site Identity: 6.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 40 N.A. N.A. 40 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 6 42 12 6 6 12 0 0 0 6 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 6 36 6 36 6 0 0 6 6 0 % D
% Glu: 12 18 18 12 0 12 24 6 24 24 18 12 6 53 18 % E
% Phe: 0 0 0 0 0 0 0 6 0 0 0 6 0 0 6 % F
% Gly: 6 0 12 0 0 0 0 0 0 0 0 6 53 12 0 % G
% His: 0 0 0 6 0 6 6 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 12 0 6 0 0 0 6 6 0 6 0 0 0 % I
% Lys: 0 59 48 6 6 24 6 18 12 53 59 53 12 0 0 % K
% Leu: 6 6 0 0 0 0 0 0 0 6 0 0 0 12 48 % L
% Met: 0 0 0 6 6 0 6 0 0 0 0 0 6 0 6 % M
% Asn: 0 0 0 6 0 0 0 0 0 0 6 0 0 0 6 % N
% Pro: 6 0 6 6 12 6 12 0 6 0 6 0 12 12 0 % P
% Gln: 6 0 0 0 6 0 0 0 0 6 0 6 0 0 6 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 6 0 0 0 36 6 0 6 0 0 6 0 % S
% Thr: 53 12 0 0 12 0 6 12 6 0 6 0 0 0 0 % T
% Val: 12 6 0 12 36 42 0 6 6 0 0 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 6 0 0 0 0 0 0 6 6 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _