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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX46 All Species: 41.52
Human Site: S296 Identified Species: 57.08
UniProt: Q7L014 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L014 NP_055644.2 1031 117362 S296 Q D A M E Y S S E E E E V D L
Chimpanzee Pan troglodytes XP_517939 1173 133261 S438 Q D A M E Y S S E E E E V D L
Rhesus Macaque Macaca mulatta XP_001109331 1031 117356 S296 Q D A M E Y S S E E E E V D L
Dog Lupus familis XP_531911 1031 117344 S296 Q D A M E Y S S E E E E V D L
Cat Felis silvestris
Mouse Mus musculus Q569Z5 1032 117430 S296 Q D A M E Y S S E E E E V D L
Rat Rattus norvegicus Q62780 1032 117367 S296 Q D A M E Y S S E E E E V D L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510706 974 110456 S239 Q D A M E Y S S E E E E V D L
Chicken Gallus gallus Q5F485 944 103035 T228 H E E I T S L T P Q Q V V E L
Frog Xenopus laevis Q7ZY47 947 104061 Q227 A I T S Q T P Q Q I T E L R H
Zebra Danio Brachydanio rerio Q4TVV3 1018 115121 S264 Q D A M E Y S S E E E E V D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573020 1224 136263 S434 M D S L E Y S S E D E L E D I
Honey Bee Apis mellifera XP_001122722 1018 114528 S280 Q D G L E Y S S E E E G E N L
Nematode Worm Caenorhab. elegans NP_001033411 970 109887 M229 E N E D N M D M V I D D F D I
Sea Urchin Strong. purpuratus XP_784902 869 99209 K195 R L E E E M Q K R R E R I E R
Poplar Tree Populus trichocarpa XP_002301895 1112 128539 N394 S D Y G D L E N G E D P L E E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8H0U8 1166 133015 A353 K P E N D G D A K M V D L E N
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SH33 1194 131283 G484 Y F S D D D Y G Y E A D G T D
Conservation
Percent
Protein Identity: 100 87.8 99.9 99.8 N.A. 98.8 98.6 N.A. 89.6 29.7 30.2 83 N.A. 49.6 63.8 47.8 54.5
Protein Similarity: 100 87.8 99.9 99.8 N.A. 99.5 99.3 N.A. 92.5 45.7 48.2 90.1 N.A. 62.9 75.9 65.9 65.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 13.3 6.6 100 N.A. 53.3 66.6 6.6 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 53.3 26.6 100 N.A. 80 80 40 33.3
Percent
Protein Identity: 43.9 N.A. N.A. 43.3 N.A. 41.3
Protein Similarity: 60.1 N.A. N.A. 58.5 N.A. 56.2
P-Site Identity: 13.3 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 46.6 N.A. N.A. 46.6 N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 6 0 48 0 0 0 0 6 0 0 6 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 65 0 12 18 6 12 0 0 6 12 18 0 59 6 % D
% Glu: 6 6 24 6 65 0 6 0 59 65 65 53 12 24 6 % E
% Phe: 0 6 0 0 0 0 0 0 0 0 0 0 6 0 0 % F
% Gly: 0 0 6 6 0 6 0 6 6 0 0 6 6 0 0 % G
% His: 6 0 0 0 0 0 0 0 0 0 0 0 0 0 6 % H
% Ile: 0 6 0 6 0 0 0 0 0 12 0 0 6 0 12 % I
% Lys: 6 0 0 0 0 0 0 6 6 0 0 0 0 0 0 % K
% Leu: 0 6 0 12 0 6 6 0 0 0 0 6 18 0 59 % L
% Met: 6 0 0 48 0 12 0 6 0 6 0 0 0 0 0 % M
% Asn: 0 6 0 6 6 0 0 6 0 0 0 0 0 6 6 % N
% Pro: 0 6 0 0 0 0 6 0 6 0 0 6 0 0 0 % P
% Gln: 53 0 0 0 6 0 6 6 6 6 6 0 0 0 0 % Q
% Arg: 6 0 0 0 0 0 0 0 6 6 0 6 0 6 6 % R
% Ser: 6 0 12 6 0 6 59 59 0 0 0 0 0 0 0 % S
% Thr: 0 0 6 0 6 6 0 6 0 0 6 0 0 6 0 % T
% Val: 0 0 0 0 0 0 0 0 6 0 6 6 53 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 6 0 6 0 0 59 6 0 6 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _