KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX46
All Species:
42.73
Human Site:
S346
Identified Species:
58.75
UniProt:
Q7L014
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L014
NP_055644.2
1031
117362
S346
V
P
E
L
A
K
M
S
Q
E
E
V
N
V
F
Chimpanzee
Pan troglodytes
XP_517939
1173
133261
S488
V
P
E
L
A
K
M
S
Q
E
E
V
N
V
F
Rhesus Macaque
Macaca mulatta
XP_001109331
1031
117356
S346
V
P
E
L
A
K
M
S
Q
E
E
V
N
V
F
Dog
Lupus familis
XP_531911
1031
117344
S346
V
P
E
L
A
K
M
S
Q
E
E
V
N
V
F
Cat
Felis silvestris
Mouse
Mus musculus
Q569Z5
1032
117430
S346
V
P
E
L
A
K
M
S
Q
E
E
V
N
V
F
Rat
Rattus norvegicus
Q62780
1032
117367
S346
V
P
E
L
A
K
M
S
Q
E
E
V
N
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510706
974
110456
S289
V
P
E
L
A
K
M
S
L
E
E
V
N
I
M
Chicken
Gallus gallus
Q5F485
944
103035
Q280
Y
T
Q
P
T
P
I
Q
C
Q
G
V
P
V
A
Frog
Xenopus laevis
Q7ZY47
947
104061
Q277
Y
T
Q
P
T
P
I
Q
C
Q
G
I
P
V
A
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
S314
V
P
E
L
A
R
M
S
P
E
E
V
S
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573020
1224
136263
T484
V
P
E
L
T
R
M
T
A
A
D
V
E
K
Y
Honey Bee
Apis mellifera
XP_001122722
1018
114528
T330
V
P
E
I
A
R
M
T
P
E
E
V
E
A
Y
Nematode Worm
Caenorhab. elegans
NP_001033411
970
109887
T278
T
E
E
I
R
R
M
T
K
A
E
V
K
A
Y
Sea Urchin
Strong. purpuratus
XP_784902
869
99209
D244
K
W
S
L
E
D
D
D
D
A
D
D
E
A
E
Poplar Tree
Populus trichocarpa
XP_002301895
1112
128539
M446
E
V
K
E
I
S
R
M
T
P
E
E
V
V
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0U8
1166
133015
M503
E
V
K
D
I
S
R
M
T
Q
E
E
V
N
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
S535
P
Y
E
L
S
H
M
S
E
E
E
L
A
E
L
Conservation
Percent
Protein Identity:
100
87.8
99.9
99.8
N.A.
98.8
98.6
N.A.
89.6
29.7
30.2
83
N.A.
49.6
63.8
47.8
54.5
Protein Similarity:
100
87.8
99.9
99.8
N.A.
99.5
99.3
N.A.
92.5
45.7
48.2
90.1
N.A.
62.9
75.9
65.9
65.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
80
13.3
6.6
66.6
N.A.
40
53.3
26.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
33.3
33.3
86.6
N.A.
66.6
80
60
13.3
Percent
Protein Identity:
43.9
N.A.
N.A.
43.3
N.A.
41.3
Protein Similarity:
60.1
N.A.
N.A.
58.5
N.A.
56.2
P-Site Identity:
13.3
N.A.
N.A.
6.6
N.A.
40
P-Site Similarity:
20
N.A.
N.A.
20
N.A.
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
53
0
0
0
6
18
0
0
6
18
18
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
0
0
0
6
0
6
6
6
6
0
12
6
0
0
0
% D
% Glu:
12
6
71
6
6
0
0
0
6
59
77
12
18
12
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
36
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
12
0
12
0
0
0
0
6
0
6
0
% I
% Lys:
6
0
12
0
0
42
0
0
6
0
0
0
6
6
0
% K
% Leu:
0
0
0
65
0
0
0
0
6
0
0
6
0
0
6
% L
% Met:
0
0
0
0
0
0
71
12
0
0
0
0
0
0
6
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
42
6
0
% N
% Pro:
6
59
0
12
0
12
0
0
12
6
0
0
12
0
0
% P
% Gln:
0
0
12
0
0
0
0
12
36
18
0
0
0
0
0
% Q
% Arg:
0
0
0
0
6
24
12
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
6
0
6
12
0
53
0
0
0
0
6
0
0
% S
% Thr:
6
12
0
0
18
0
0
18
12
0
0
0
0
0
6
% T
% Val:
59
12
0
0
0
0
0
0
0
0
0
71
12
53
0
% V
% Trp:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
6
0
0
0
0
0
0
0
0
0
0
0
0
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _