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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX46
All Species:
31.21
Human Site:
S439
Identified Species:
42.92
UniProt:
Q7L014
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L014
NP_055644.2
1031
117362
S439
R
H
I
M
D
Q
R
S
L
E
E
G
E
G
P
Chimpanzee
Pan troglodytes
XP_517939
1173
133261
S581
R
H
I
M
D
Q
R
S
L
E
E
G
E
G
P
Rhesus Macaque
Macaca mulatta
XP_001109331
1031
117356
S439
R
H
I
M
D
Q
R
S
L
E
E
G
E
G
P
Dog
Lupus familis
XP_531911
1031
117344
S439
R
H
I
M
D
Q
R
S
L
E
E
G
E
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q569Z5
1032
117430
S439
R
H
I
M
D
Q
R
S
L
E
E
G
E
G
P
Rat
Rattus norvegicus
Q62780
1032
117367
S439
R
H
I
M
D
Q
R
S
L
E
E
G
E
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510706
974
110456
S382
R
H
I
M
D
Q
R
S
L
E
E
G
E
G
P
Chicken
Gallus gallus
Q5F485
944
103035
A372
S
M
W
E
Q
A
K
A
L
Q
E
G
A
E
I
Frog
Xenopus laevis
Q7ZY47
947
104061
A369
S
M
W
E
Q
A
K
A
L
Q
E
G
A
E
I
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
P407
R
H
I
L
D
Q
R
P
V
G
E
A
E
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573020
1224
136263
S577
R
H
I
L
D
Q
P
S
M
E
D
G
D
G
A
Honey Bee
Apis mellifera
XP_001122722
1018
114528
P423
R
H
I
L
D
Q
P
P
L
A
D
G
D
G
P
Nematode Worm
Caenorhab. elegans
NP_001033411
970
109887
E371
R
H
I
L
D
Q
P
E
L
E
E
G
D
G
P
Sea Urchin
Strong. purpuratus
XP_784902
869
99209
E336
D
A
M
E
Y
S
S
E
E
E
K
E
S
N
L
Poplar Tree
Populus trichocarpa
XP_002301895
1112
128539
P539
R
H
I
K
D
Q
P
P
V
E
A
G
E
G
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0U8
1166
133015
P596
R
H
I
K
D
Q
P
P
V
E
A
G
D
G
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
P628
R
H
V
K
D
Q
D
P
V
T
G
D
D
G
A
Conservation
Percent
Protein Identity:
100
87.8
99.9
99.8
N.A.
98.8
98.6
N.A.
89.6
29.7
30.2
83
N.A.
49.6
63.8
47.8
54.5
Protein Similarity:
100
87.8
99.9
99.8
N.A.
99.5
99.3
N.A.
92.5
45.7
48.2
90.1
N.A.
62.9
75.9
65.9
65.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
20
20
66.6
N.A.
60
60
73.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
40
40
80
N.A.
86.6
80
86.6
20
Percent
Protein Identity:
43.9
N.A.
N.A.
43.3
N.A.
41.3
Protein Similarity:
60.1
N.A.
N.A.
58.5
N.A.
56.2
P-Site Identity:
66.6
N.A.
N.A.
60
N.A.
33.3
P-Site Similarity:
73.3
N.A.
N.A.
73.3
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
0
0
12
0
12
0
6
12
6
12
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
0
0
83
0
6
0
0
0
12
6
30
0
0
% D
% Glu:
0
0
0
18
0
0
0
12
6
71
65
6
53
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
6
6
83
0
83
0
% G
% His:
0
83
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
77
0
0
0
0
0
0
0
0
0
0
0
12
% I
% Lys:
0
0
0
18
0
0
12
0
0
0
6
0
0
0
0
% K
% Leu:
0
0
0
24
0
0
0
0
65
0
0
0
0
0
6
% L
% Met:
0
12
6
42
0
0
0
0
6
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% N
% Pro:
0
0
0
0
0
0
30
30
0
0
0
0
0
0
71
% P
% Gln:
0
0
0
0
12
83
0
0
0
12
0
0
0
0
0
% Q
% Arg:
83
0
0
0
0
0
48
0
0
0
0
0
0
0
0
% R
% Ser:
12
0
0
0
0
6
6
48
0
0
0
0
6
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% T
% Val:
0
0
6
0
0
0
0
0
24
0
0
0
0
0
0
% V
% Trp:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _