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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX46
All Species:
26.06
Human Site:
S52
Identified Species:
35.83
UniProt:
Q7L014
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L014
NP_055644.2
1031
117362
S52
R
D
R
R
R
E
R
S
R
S
R
D
K
R
R
Chimpanzee
Pan troglodytes
XP_517939
1173
133261
S194
R
D
R
R
R
E
R
S
R
S
R
D
K
R
R
Rhesus Macaque
Macaca mulatta
XP_001109331
1031
117356
S52
R
D
R
R
R
E
R
S
R
S
R
D
K
R
R
Dog
Lupus familis
XP_531911
1031
117344
S52
R
D
R
R
R
E
R
S
R
S
R
D
K
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q569Z5
1032
117430
S52
R
D
R
R
R
E
R
S
R
S
R
D
K
R
R
Rat
Rattus norvegicus
Q62780
1032
117367
S52
R
D
R
R
R
E
R
S
R
S
R
D
K
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510706
974
110456
K53
S
R
S
A
S
P
S
K
N
K
K
T
E
T
R
Chicken
Gallus gallus
Q5F485
944
103035
G52
S
A
A
F
A
K
S
G
P
P
Q
L
P
S
F
Frog
Xenopus laevis
Q7ZY47
947
104061
L53
Y
G
S
T
S
N
Q
L
P
S
F
Y
K
I
G
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
R52
R
R
E
R
S
R
S
R
E
R
R
R
S
R
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573020
1224
136263
S89
D
D
K
R
R
K
C
S
R
S
K
D
Y
E
K
Honey Bee
Apis mellifera
XP_001122722
1018
114528
R55
K
G
R
H
R
E
R
R
S
R
S
R
D
R
D
Nematode Worm
Caenorhab. elegans
NP_001033411
970
109887
E54
R
E
R
D
T
D
R
E
K
T
R
D
R
E
K
Sea Urchin
Strong. purpuratus
XP_784902
869
99209
K24
D
A
D
N
D
S
S
K
K
K
R
S
P
E
R
Poplar Tree
Populus trichocarpa
XP_002301895
1112
128539
D78
R
E
K
E
K
H
K
D
R
D
R
D
R
D
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0U8
1166
133015
D66
S
E
D
D
Y
D
R
D
D
D
E
E
R
E
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
R62
R
D
R
G
R
D
G
R
D
R
D
S
Y
R
R
Conservation
Percent
Protein Identity:
100
87.8
99.9
99.8
N.A.
98.8
98.6
N.A.
89.6
29.7
30.2
83
N.A.
49.6
63.8
47.8
54.5
Protein Similarity:
100
87.8
99.9
99.8
N.A.
99.5
99.3
N.A.
92.5
45.7
48.2
90.1
N.A.
62.9
75.9
65.9
65.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
0
13.3
26.6
N.A.
46.6
33.3
33.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
13.3
20
26.6
N.A.
73.3
40
73.3
20
Percent
Protein Identity:
43.9
N.A.
N.A.
43.3
N.A.
41.3
Protein Similarity:
60.1
N.A.
N.A.
58.5
N.A.
56.2
P-Site Identity:
26.6
N.A.
N.A.
6.6
N.A.
40
P-Site Similarity:
66.6
N.A.
N.A.
40
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
6
6
6
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% C
% Asp:
12
48
12
12
6
18
0
12
12
12
6
53
6
6
6
% D
% Glu:
0
18
6
6
0
42
0
6
6
0
6
6
6
24
6
% E
% Phe:
0
0
0
6
0
0
0
0
0
0
6
0
0
0
6
% F
% Gly:
0
12
0
6
0
0
6
6
0
0
0
0
0
0
6
% G
% His:
0
0
0
6
0
6
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% I
% Lys:
6
0
12
0
6
12
6
12
12
12
12
0
42
0
24
% K
% Leu:
0
0
0
0
0
0
0
6
0
0
0
6
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
6
0
6
0
0
6
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
6
0
0
12
6
0
0
12
0
0
% P
% Gln:
0
0
0
0
0
0
6
0
0
0
6
0
0
0
0
% Q
% Arg:
59
12
53
48
53
6
53
18
48
18
59
12
18
53
53
% R
% Ser:
18
0
12
0
18
6
24
42
6
48
6
12
6
6
0
% S
% Thr:
0
0
0
6
6
0
0
0
0
6
0
6
0
6
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
6
0
0
0
0
0
0
6
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _