KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX46
All Species:
43.03
Human Site:
S621
Identified Species:
59.17
UniProt:
Q7L014
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L014
NP_055644.2
1031
117362
S621
G
H
Y
Q
E
S
G
S
V
I
I
F
V
D
K
Chimpanzee
Pan troglodytes
XP_517939
1173
133261
S763
G
H
Y
Q
E
S
G
S
V
I
I
F
V
D
K
Rhesus Macaque
Macaca mulatta
XP_001109331
1031
117356
S621
G
H
Y
Q
E
S
G
S
V
I
I
F
V
D
K
Dog
Lupus familis
XP_531911
1031
117344
S621
G
H
Y
Q
E
S
G
S
V
I
I
F
V
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q569Z5
1032
117430
S621
G
H
Y
Q
E
S
G
S
V
I
I
F
V
D
K
Rat
Rattus norvegicus
Q62780
1032
117367
S621
G
H
Y
Q
E
S
G
S
V
I
I
F
V
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510706
974
110456
S564
G
H
Y
Q
E
S
G
S
V
I
I
F
V
D
K
Chicken
Gallus gallus
Q5F485
944
103035
V540
D
Q
S
E
R
N
K
V
I
S
E
F
K
K
K
Frog
Xenopus laevis
Q7ZY47
947
104061
I546
S
D
F
K
K
K
S
I
P
V
L
V
A
T
D
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
S589
G
H
Y
Q
E
K
G
S
V
I
I
F
V
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573020
1224
136263
S759
G
I
Y
Q
E
A
G
S
I
I
V
F
V
D
K
Honey Bee
Apis mellifera
XP_001122722
1018
114528
S605
G
H
Y
Q
D
K
G
S
A
I
I
F
V
D
K
Nematode Worm
Caenorhab. elegans
NP_001033411
970
109887
S553
G
M
Y
Y
E
E
G
S
S
I
V
F
V
D
K
Sea Urchin
Strong. purpuratus
XP_784902
869
99209
M491
D
G
P
I
T
L
I
M
T
P
T
R
E
L
A
Poplar Tree
Populus trichocarpa
XP_002301895
1112
128539
K721
G
E
W
Y
Q
K
G
K
I
L
I
F
V
Q
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0U8
1166
133015
K778
G
E
W
S
E
K
G
K
I
L
V
F
V
Q
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
E800
K
K
F
N
R
L
L
E
L
L
G
E
L
Y
A
Conservation
Percent
Protein Identity:
100
87.8
99.9
99.8
N.A.
98.8
98.6
N.A.
89.6
29.7
30.2
83
N.A.
49.6
63.8
47.8
54.5
Protein Similarity:
100
87.8
99.9
99.8
N.A.
99.5
99.3
N.A.
92.5
45.7
48.2
90.1
N.A.
62.9
75.9
65.9
65.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
13.3
0
93.3
N.A.
73.3
80
66.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
33.3
33.3
93.3
N.A.
93.3
86.6
73.3
0
Percent
Protein Identity:
43.9
N.A.
N.A.
43.3
N.A.
41.3
Protein Similarity:
60.1
N.A.
N.A.
58.5
N.A.
56.2
P-Site Identity:
33.3
N.A.
N.A.
33.3
N.A.
0
P-Site Similarity:
60
N.A.
N.A.
60
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
6
0
0
6
0
0
0
6
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
6
0
0
6
0
0
0
0
0
0
0
0
65
6
% D
% Glu:
0
12
0
6
65
6
0
6
0
0
6
6
6
0
0
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
0
83
0
0
0
% F
% Gly:
77
6
0
0
0
0
77
0
0
0
6
0
0
0
0
% G
% His:
0
53
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
6
0
6
0
0
6
6
24
65
59
0
0
0
0
% I
% Lys:
6
6
0
6
6
30
6
12
0
0
0
0
6
6
71
% K
% Leu:
0
0
0
0
0
12
6
0
6
18
6
0
6
6
0
% L
% Met:
0
6
0
0
0
0
0
6
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
6
0
6
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
6
0
0
0
0
0
6
6
0
0
0
0
0
% P
% Gln:
0
6
0
59
6
0
0
0
0
0
0
0
0
12
0
% Q
% Arg:
0
0
0
0
12
0
0
0
0
0
0
6
0
0
0
% R
% Ser:
6
0
6
6
0
42
6
65
6
6
0
0
0
0
12
% S
% Thr:
0
0
0
0
6
0
0
0
6
0
6
0
0
6
0
% T
% Val:
0
0
0
0
0
0
0
6
48
6
18
6
77
0
0
% V
% Trp:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
65
12
0
0
0
0
0
0
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _