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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX46
All Species:
36.36
Human Site:
S754
Identified Species:
50
UniProt:
Q7L014
Number Species:
16
Phosphosite Substitution
Charge Score:
0.19
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L014
NP_055644.2
1031
117362
S754
P
D
L
E
K
L
W
S
D
F
K
D
Q
Q
K
Chimpanzee
Pan troglodytes
XP_517939
1173
133261
S896
P
D
L
E
K
L
W
S
D
F
K
D
Q
Q
K
Rhesus Macaque
Macaca mulatta
XP_001109331
1031
117356
S754
P
D
L
E
K
L
W
S
D
F
K
D
Q
Q
K
Dog
Lupus familis
XP_531911
1031
117344
S754
P
D
L
E
K
L
W
S
D
F
K
D
Q
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q569Z5
1032
117430
S754
P
D
L
E
K
L
W
S
D
F
K
D
Q
Q
K
Rat
Rattus norvegicus
Q62780
1032
117367
S754
P
D
L
E
K
L
W
S
D
F
K
D
Q
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510706
974
110456
S697
A
D
L
E
K
L
W
S
D
F
K
D
Q
Q
K
Chicken
Gallus gallus
Q5F485
944
103035
G667
Y
R
E
R
P
G
L
G
S
E
S
S
D
R
G
Frog
Xenopus laevis
Q7ZY47
947
104061
S678
G
T
G
G
N
V
M
S
N
Y
E
A
F
K
P
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
T722
A
E
L
E
Q
L
W
T
N
F
K
E
Q
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573020
1224
136263
T892
A
E
L
Q
A
L
W
T
E
Y
K
A
L
Q
E
Honey Bee
Apis mellifera
XP_001122722
1018
114528
E738
E
P
L
R
Q
L
W
E
G
Y
K
A
R
Q
A
Nematode Worm
Caenorhab. elegans
NP_001033411
970
109887
F687
P
A
D
L
K
A
M
F
E
R
F
K
S
E
M
Sea Urchin
Strong. purpuratus
XP_784902
869
99209
L615
E
A
L
A
R
K
I
L
T
K
P
I
E
V
Q
Poplar Tree
Populus trichocarpa
XP_002301895
1112
128539
D854
Q
D
L
K
A
L
A
D
G
F
M
A
K
V
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0U8
1166
133015
D911
D
D
L
K
A
L
A
D
G
F
M
V
K
V
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
A929
C
A
S
G
I
A
K
A
L
E
Q
S
G
Q
P
Conservation
Percent
Protein Identity:
100
87.8
99.9
99.8
N.A.
98.8
98.6
N.A.
89.6
29.7
30.2
83
N.A.
49.6
63.8
47.8
54.5
Protein Similarity:
100
87.8
99.9
99.8
N.A.
99.5
99.3
N.A.
92.5
45.7
48.2
90.1
N.A.
62.9
75.9
65.9
65.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
0
6.6
60
N.A.
33.3
33.3
13.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
6.6
40
93.3
N.A.
73.3
53.3
26.6
26.6
Percent
Protein Identity:
43.9
N.A.
N.A.
43.3
N.A.
41.3
Protein Similarity:
60.1
N.A.
N.A.
58.5
N.A.
56.2
P-Site Identity:
26.6
N.A.
N.A.
33.3
N.A.
6.6
P-Site Similarity:
40
N.A.
N.A.
46.6
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
18
0
6
18
12
12
6
0
0
0
24
0
0
6
% A
% Cys:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
53
6
0
0
0
0
12
42
0
0
42
6
0
0
% D
% Glu:
12
12
6
48
0
0
0
6
12
12
6
6
6
6
6
% E
% Phe:
0
0
0
0
0
0
0
6
0
59
6
0
6
0
0
% F
% Gly:
6
0
6
12
0
6
0
6
18
0
0
0
6
0
6
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
6
0
6
0
0
0
0
6
0
0
0
% I
% Lys:
0
0
0
12
48
6
6
0
0
6
59
6
12
6
53
% K
% Leu:
0
0
77
6
0
71
6
6
6
0
0
0
6
0
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
12
0
0
0
6
% M
% Asn:
0
0
0
0
6
0
0
0
12
0
0
0
0
0
6
% N
% Pro:
42
6
0
0
6
0
0
0
0
0
6
0
0
0
12
% P
% Gln:
6
0
0
6
12
0
0
0
0
0
6
0
48
65
6
% Q
% Arg:
0
6
0
12
6
0
0
0
0
6
0
0
6
6
0
% R
% Ser:
0
0
6
0
0
0
0
48
6
0
6
12
6
0
0
% S
% Thr:
0
6
0
0
0
0
0
12
6
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
6
0
0
0
0
0
6
0
18
0
% V
% Trp:
0
0
0
0
0
0
59
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
0
0
0
0
0
18
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _