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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX46 All Species: 33.64
Human Site: S823 Identified Species: 46.25
UniProt: Q7L014 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L014 NP_055644.2 1031 117362 S823 Q I E S M F N S K K R V K D M
Chimpanzee Pan troglodytes XP_517939 1173 133261 S965 Q I E S M F N S K K R V K D M
Rhesus Macaque Macaca mulatta XP_001109331 1031 117356 S823 Q I E S M F N S K K R V K D M
Dog Lupus familis XP_531911 1031 117344 S823 Q I E S M F N S K K R V K D M
Cat Felis silvestris
Mouse Mus musculus Q569Z5 1032 117430 S823 Q I E S M F N S K K R V K D M
Rat Rattus norvegicus Q62780 1032 117367 S823 Q I E S M F N S K K R V K D M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510706 974 110456 S766 Q I E S M F N S K K R V K D M
Chicken Gallus gallus Q5F485 944 103035 S737 S G W T S A G S L N S V P T S
Frog Xenopus laevis Q7ZY47 947 104061 S745 V P S A H P P S G K L P A E A
Zebra Danio Brachydanio rerio Q4TVV3 1018 115121 S791 Q I E S M F N S K K R V K D F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573020 1224 136263 A962 Q I E Q I F A A K R T V K D T
Honey Bee Apis mellifera XP_001122722 1018 114528 P807 Q I E S M L A P K R T V R E I
Nematode Worm Caenorhab. elegans NP_001033411 970 109887 I754 E E Q L S S M I K T K R R V V
Sea Urchin Strong. purpuratus XP_784902 869 99209 D677 S A D L L L K D L M K A S Y P
Poplar Tree Populus trichocarpa XP_002301895 1112 128539 G919 E V V R K S V G D V S Q Q T A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8H0U8 1166 133015 K973 D E N D V V R K A G G G E I S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SH33 1194 131283 E991 K T H K A E G E E D D V K E D
Conservation
Percent
Protein Identity: 100 87.8 99.9 99.8 N.A. 98.8 98.6 N.A. 89.6 29.7 30.2 83 N.A. 49.6 63.8 47.8 54.5
Protein Similarity: 100 87.8 99.9 99.8 N.A. 99.5 99.3 N.A. 92.5 45.7 48.2 90.1 N.A. 62.9 75.9 65.9 65.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 13.3 13.3 93.3 N.A. 53.3 46.6 6.6 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 20 26.6 93.3 N.A. 73.3 73.3 40 20
Percent
Protein Identity: 43.9 N.A. N.A. 43.3 N.A. 41.3
Protein Similarity: 60.1 N.A. N.A. 58.5 N.A. 56.2
P-Site Identity: 0 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 20 N.A. N.A. 13.3 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 0 6 6 6 12 6 6 0 0 6 6 0 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 0 6 6 0 0 0 6 6 6 6 0 0 53 6 % D
% Glu: 12 12 59 0 0 6 0 6 6 0 0 0 6 18 0 % E
% Phe: 0 0 0 0 0 53 0 0 0 0 0 0 0 0 6 % F
% Gly: 0 6 0 0 0 0 12 6 6 6 6 6 0 0 0 % G
% His: 0 0 6 0 6 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 59 0 0 6 0 0 6 0 0 0 0 0 6 6 % I
% Lys: 6 0 0 6 6 0 6 6 65 53 12 0 59 0 0 % K
% Leu: 0 0 0 12 6 12 0 0 12 0 6 0 0 0 0 % L
% Met: 0 0 0 0 53 0 6 0 0 6 0 0 0 0 42 % M
% Asn: 0 0 6 0 0 0 48 0 0 6 0 0 0 0 0 % N
% Pro: 0 6 0 0 0 6 6 6 0 0 0 6 6 0 6 % P
% Gln: 59 0 6 6 0 0 0 0 0 0 0 6 6 0 0 % Q
% Arg: 0 0 0 6 0 0 6 0 0 12 48 6 12 0 0 % R
% Ser: 12 0 6 53 12 12 0 59 0 0 12 0 6 0 12 % S
% Thr: 0 6 0 6 0 0 0 0 0 6 12 0 0 12 6 % T
% Val: 6 6 6 0 6 6 6 0 0 6 0 71 0 6 6 % V
% Trp: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _