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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX46 All Species: 30
Human Site: S87 Identified Species: 41.25
UniProt: Q7L014 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L014 NP_055644.2 1031 117362 S87 R E R R R S R S R D R R R S R
Chimpanzee Pan troglodytes XP_517939 1173 133261 S229 R E R R R S R S R D R R R S R
Rhesus Macaque Macaca mulatta XP_001109331 1031 117356 S87 R E R R R S R S R D R R R S R
Dog Lupus familis XP_531911 1031 117344 S87 R E R R R S R S R D R R R S R
Cat Felis silvestris
Mouse Mus musculus Q569Z5 1032 117430 S87 R E R R R S R S R D R R R S R
Rat Rattus norvegicus Q62780 1032 117367 S87 R E R R R S R S R D R R R S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510706 974 110456 E88 E D K E E E K E K D V S N F D
Chicken Gallus gallus Q5F485 944 103035 D87 E E D N S N V D L P Y I P A E
Frog Xenopus laevis Q7ZY47 947 104061 I88 S N V D L P Y I P A E N S P T
Zebra Danio Brachydanio rerio Q4TVV3 1018 115121 G87 R S K S R S R G R S K E K P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573020 1224 136263 E124 R Q R E K E R E R E K E K E R
Honey Bee Apis mellifera XP_001122722 1018 114528 S90 K E K R L T G S K S S R S G K
Nematode Worm Caenorhab. elegans NP_001033411 970 109887 E89 E S R N D T E E V M K M K E A
Sea Urchin Strong. purpuratus XP_784902 869 99209 S59 E R S R R S R S K E R E R D R
Poplar Tree Populus trichocarpa XP_002301895 1112 128539 K113 R D K D R E E K K D R D K D R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8H0U8 1166 133015 S101 E R R K S S D S E D D V E E E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SH33 1194 131283 R97 D R R R S R D R G L D R L R S
Conservation
Percent
Protein Identity: 100 87.8 99.9 99.8 N.A. 98.8 98.6 N.A. 89.6 29.7 30.2 83 N.A. 49.6 63.8 47.8 54.5
Protein Similarity: 100 87.8 99.9 99.8 N.A. 99.5 99.3 N.A. 92.5 45.7 48.2 90.1 N.A. 62.9 75.9 65.9 65.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 6.6 0 33.3 N.A. 33.3 26.6 6.6 53.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 33.3 20 0 53.3 N.A. 66.6 60 26.6 66.6
Percent
Protein Identity: 43.9 N.A. N.A. 43.3 N.A. 41.3
Protein Similarity: 60.1 N.A. N.A. 58.5 N.A. 56.2
P-Site Identity: 33.3 N.A. N.A. 26.6 N.A. 20
P-Site Similarity: 60 N.A. N.A. 33.3 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 6 0 0 0 6 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 12 6 12 6 0 12 6 0 53 12 6 0 12 6 % D
% Glu: 30 48 0 12 6 18 12 18 6 12 6 18 6 18 18 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % F
% Gly: 0 0 0 0 0 0 6 6 6 0 0 0 0 6 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 6 0 0 0 6 0 0 0 % I
% Lys: 6 0 24 6 6 0 6 6 24 0 18 0 24 0 6 % K
% Leu: 0 0 0 0 12 0 0 0 6 6 0 0 6 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 6 0 6 0 0 0 % M
% Asn: 0 6 0 12 0 6 0 0 0 0 0 6 6 0 0 % N
% Pro: 0 0 0 0 0 6 0 0 6 6 0 0 6 12 0 % P
% Gln: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 53 18 59 53 53 6 53 6 48 0 48 48 42 6 53 % R
% Ser: 6 12 6 6 18 53 0 53 0 12 6 6 12 36 6 % S
% Thr: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 6 % T
% Val: 0 0 6 0 0 0 6 0 6 0 6 6 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 6 0 0 0 6 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _