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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX46
All Species:
41.82
Human Site:
S959
Identified Species:
57.5
UniProt:
Q7L014
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L014
NP_055644.2
1031
117362
S959
K
E
A
L
Q
R
I
S
E
Y
S
E
A
A
I
Chimpanzee
Pan troglodytes
XP_517939
1173
133261
S1101
K
E
A
L
Q
R
I
S
E
Y
S
E
A
A
I
Rhesus Macaque
Macaca mulatta
XP_001109331
1031
117356
S959
K
E
A
L
Q
R
I
S
E
Y
S
E
A
A
I
Dog
Lupus familis
XP_531911
1031
117344
S959
K
E
A
L
Q
R
I
S
E
Y
S
E
A
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q569Z5
1032
117430
S960
K
E
A
L
Q
R
I
S
E
Y
S
E
A
A
I
Rat
Rattus norvegicus
Q62780
1032
117367
S960
K
E
A
L
Q
R
I
S
E
Y
S
E
A
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510706
974
110456
S902
K
E
A
L
Q
R
I
S
E
Y
S
E
A
A
I
Chicken
Gallus gallus
Q5F485
944
103035
G861
Q
H
H
G
E
G
G
G
R
Y
S
D
A
Y
R
Frog
Xenopus laevis
Q7ZY47
947
104061
R871
S
R
D
G
E
S
R
R
D
G
S
R
D
G
G
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
G946
K
E
A
L
Q
R
I
G
E
Y
S
E
A
A
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573020
1224
136263
S1152
K
E
A
L
A
Q
I
S
E
Y
S
E
A
G
L
Honey Bee
Apis mellifera
XP_001122722
1018
114528
S945
K
E
A
L
A
Q
I
S
E
Y
S
E
A
G
L
Nematode Worm
Caenorhab. elegans
NP_001033411
970
109887
A898
R
E
S
V
G
H
V
A
E
L
A
E
V
G
I
Sea Urchin
Strong. purpuratus
XP_784902
869
99209
Q798
M
W
S
L
Y
C
N
Q
Q
K
S
E
G
K
E
Poplar Tree
Populus trichocarpa
XP_002301895
1112
128539
S1040
K
E
T
L
G
P
I
S
D
W
T
G
A
A
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0U8
1166
133015
S1094
K
E
T
L
G
P
I
S
E
W
T
G
A
A
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
L1120
R
T
N
V
A
K
I
L
E
A
T
G
T
S
I
Conservation
Percent
Protein Identity:
100
87.8
99.9
99.8
N.A.
98.8
98.6
N.A.
89.6
29.7
30.2
83
N.A.
49.6
63.8
47.8
54.5
Protein Similarity:
100
87.8
99.9
99.8
N.A.
99.5
99.3
N.A.
92.5
45.7
48.2
90.1
N.A.
62.9
75.9
65.9
65.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
20
6.6
93.3
N.A.
73.3
73.3
26.6
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
40
20
93.3
N.A.
86.6
86.6
66.6
33.3
Percent
Protein Identity:
43.9
N.A.
N.A.
43.3
N.A.
41.3
Protein Similarity:
60.1
N.A.
N.A.
58.5
N.A.
56.2
P-Site Identity:
53.3
N.A.
N.A.
60
N.A.
20
P-Site Similarity:
73.3
N.A.
N.A.
73.3
N.A.
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
59
0
18
0
0
6
0
6
6
0
77
59
0
% A
% Cys:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
0
0
0
0
0
12
0
0
6
6
0
0
% D
% Glu:
0
77
0
0
12
0
0
0
77
0
0
71
0
0
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
18
6
6
12
0
6
0
18
6
24
6
% G
% His:
0
6
6
0
0
6
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
77
0
0
0
0
0
0
0
71
% I
% Lys:
71
0
0
0
0
6
0
0
0
6
0
0
0
6
0
% K
% Leu:
0
0
0
77
0
0
0
6
0
6
0
0
0
0
12
% L
% Met:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
6
0
0
0
6
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% P
% Gln:
6
0
0
0
48
12
0
6
6
0
0
0
0
0
0
% Q
% Arg:
12
6
0
0
0
48
6
6
6
0
0
6
0
0
6
% R
% Ser:
6
0
12
0
0
6
0
65
0
0
77
0
0
6
0
% S
% Thr:
0
6
12
0
0
0
0
0
0
0
18
0
6
0
0
% T
% Val:
0
0
0
12
0
0
6
0
0
0
0
0
6
0
0
% V
% Trp:
0
6
0
0
0
0
0
0
0
12
0
0
0
0
0
% W
% Tyr:
0
0
0
0
6
0
0
0
0
65
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _