Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX46 All Species: 53.03
Human Site: S962 Identified Species: 72.92
UniProt: Q7L014 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L014 NP_055644.2 1031 117362 S962 L Q R I S E Y S E A A I T I R
Chimpanzee Pan troglodytes XP_517939 1173 133261 S1104 L Q R I S E Y S E A A I T I R
Rhesus Macaque Macaca mulatta XP_001109331 1031 117356 S962 L Q R I S E Y S E A A I T I R
Dog Lupus familis XP_531911 1031 117344 S962 L Q R I S E Y S E A A I T I R
Cat Felis silvestris
Mouse Mus musculus Q569Z5 1032 117430 S963 L Q R I S E Y S E A A I T I R
Rat Rattus norvegicus Q62780 1032 117367 S963 L Q R I S E Y S E A A I T I R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510706 974 110456 S905 L Q R I S E Y S E A A I T I R
Chicken Gallus gallus Q5F485 944 103035 S864 G E G G G R Y S D A Y R H G E
Frog Xenopus laevis Q7ZY47 947 104061 S874 G E S R R D G S R D G G E G R
Zebra Danio Brachydanio rerio Q4TVV3 1018 115121 S949 L Q R I G E Y S E A A I T I R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573020 1224 136263 S1155 L A Q I S E Y S E A G L T V R
Honey Bee Apis mellifera XP_001122722 1018 114528 S948 L A Q I S E Y S E A G L T V R
Nematode Worm Caenorhab. elegans NP_001033411 970 109887 A901 V G H V A E L A E V G I S V R
Sea Urchin Strong. purpuratus XP_784902 869 99209 S801 L Y C N Q Q K S E G K E V T K
Poplar Tree Populus trichocarpa XP_002301895 1112 128539 T1043 L G P I S D W T G A A I T T R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8H0U8 1166 133015 T1097 L G P I S E W T G A A I T T R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SH33 1194 131283 T1123 V A K I L E A T G T S I T T K
Conservation
Percent
Protein Identity: 100 87.8 99.9 99.8 N.A. 98.8 98.6 N.A. 89.6 29.7 30.2 83 N.A. 49.6 63.8 47.8 54.5
Protein Similarity: 100 87.8 99.9 99.8 N.A. 99.5 99.3 N.A. 92.5 45.7 48.2 90.1 N.A. 62.9 75.9 65.9 65.8
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 20 13.3 93.3 N.A. 66.6 66.6 26.6 20
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 33.3 26.6 93.3 N.A. 86.6 86.6 66.6 33.3
Percent
Protein Identity: 43.9 N.A. N.A. 43.3 N.A. 41.3
Protein Similarity: 60.1 N.A. N.A. 58.5 N.A. 56.2
P-Site Identity: 53.3 N.A. N.A. 60 N.A. 26.6
P-Site Similarity: 73.3 N.A. N.A. 73.3 N.A. 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 18 0 0 6 0 6 6 0 77 59 0 0 0 0 % A
% Cys: 0 0 6 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 12 0 0 6 6 0 0 0 0 0 % D
% Glu: 0 12 0 0 0 77 0 0 71 0 0 6 6 0 6 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 12 18 6 6 12 0 6 0 18 6 24 6 0 12 0 % G
% His: 0 0 6 0 0 0 0 0 0 0 0 0 6 0 0 % H
% Ile: 0 0 0 77 0 0 0 0 0 0 0 71 0 48 0 % I
% Lys: 0 0 6 0 0 0 6 0 0 0 6 0 0 0 12 % K
% Leu: 77 0 0 0 6 0 6 0 0 0 0 12 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 48 12 0 6 6 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 48 6 6 6 0 0 6 0 0 6 0 0 83 % R
% Ser: 0 0 6 0 65 0 0 77 0 0 6 0 6 0 0 % S
% Thr: 0 0 0 0 0 0 0 18 0 6 0 0 77 24 0 % T
% Val: 12 0 0 6 0 0 0 0 0 6 0 0 6 18 0 % V
% Trp: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % W
% Tyr: 0 6 0 0 0 0 65 0 0 0 6 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _