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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX46 All Species: 13.33
Human Site: T124 Identified Species: 18.33
UniProt: Q7L014 Number Species: 16
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q7L014 NP_055644.2 1031 117362 T124 R S R S K E K T D G G E S S K
Chimpanzee Pan troglodytes XP_517939 1173 133261 T266 R S R S K E K T D G G E S S K
Rhesus Macaque Macaca mulatta XP_001109331 1031 117356 T124 R S R S K E K T D G G E S S K
Dog Lupus familis XP_531911 1031 117344 T124 R S R S K E K T D S G E S S K
Cat Felis silvestris
Mouse Mus musculus Q569Z5 1032 117430 A124 R S R S K E K A E G G D S S K
Rat Rattus norvegicus Q62780 1032 117367 A124 R S R S K E K A E G G D S S K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510706 974 110456 I125 R K K A M E N I G E L K K E I
Chicken Gallus gallus Q5F485 944 103035 E124 E A F M A E V E D Q A A R D M
Frog Xenopus laevis Q7ZY47 947 104061 K125 E V E D Q A A K D M R K L E E
Zebra Danio Brachydanio rerio Q4TVV3 1018 115121 L124 Q D F D Q N T L E E E M R K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573020 1224 136263 A161 D S R R A A A A A P L I I P L
Honey Bee Apis mellifera XP_001122722 1018 114528 D127 P F D H T K L D K K R L E L E
Nematode Worm Caenorhab. elegans NP_001033411 970 109887 E126 E E L D L Q S E Q S D E K S E
Sea Urchin Strong. purpuratus XP_784902 869 99209 R96 D I E R D R V R E R D R R S R
Poplar Tree Populus trichocarpa XP_002301895 1112 128539 R150 D R E R E R E R E R E K R E R
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8H0U8 1166 133015 R138 G K D R K R D R E R E E R K D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SH33 1194 131283 R134 R D R A R V R R E G T A E S S
Conservation
Percent
Protein Identity: 100 87.8 99.9 99.8 N.A. 98.8 98.6 N.A. 89.6 29.7 30.2 83 N.A. 49.6 63.8 47.8 54.5
Protein Similarity: 100 87.8 99.9 99.8 N.A. 99.5 99.3 N.A. 92.5 45.7 48.2 90.1 N.A. 62.9 75.9 65.9 65.8
P-Site Identity: 100 100 100 93.3 N.A. 80 80 N.A. 13.3 13.3 6.6 0 N.A. 13.3 0 13.3 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 33.3 20 26.6 26.6 N.A. 13.3 13.3 26.6 20
Percent
Protein Identity: 43.9 N.A. N.A. 43.3 N.A. 41.3
Protein Similarity: 60.1 N.A. N.A. 58.5 N.A. 56.2
P-Site Identity: 0 N.A. N.A. 13.3 N.A. 26.6
P-Site Similarity: 33.3 N.A. N.A. 20 N.A. 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 0 12 12 12 12 18 6 0 6 12 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 18 12 12 18 6 0 6 6 36 0 12 12 0 6 6 % D
% Glu: 18 6 18 0 6 48 6 12 42 12 18 36 12 18 18 % E
% Phe: 0 6 12 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 6 0 0 0 0 0 0 0 6 36 36 0 0 0 0 % G
% His: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 6 0 0 0 0 0 6 0 0 0 6 6 0 6 % I
% Lys: 0 12 6 0 42 6 36 6 6 6 0 18 12 12 36 % K
% Leu: 0 0 6 0 6 0 6 6 0 0 12 6 6 6 6 % L
% Met: 0 0 0 6 6 0 0 0 0 6 0 6 0 0 6 % M
% Asn: 0 0 0 0 0 6 6 0 0 0 0 0 0 0 0 % N
% Pro: 6 0 0 0 0 0 0 0 0 6 0 0 0 6 0 % P
% Gln: 6 0 0 0 12 6 0 0 6 6 0 0 0 0 0 % Q
% Arg: 48 6 48 24 6 18 6 24 0 18 12 6 30 0 18 % R
% Ser: 0 42 0 36 0 0 6 0 0 12 0 0 36 53 6 % S
% Thr: 0 0 0 0 6 0 6 24 0 0 6 0 0 0 0 % T
% Val: 0 6 0 0 0 6 12 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _