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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX46
All Species:
48.79
Human Site:
T721
Identified Species:
67.08
UniProt:
Q7L014
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L014
NP_055644.2
1031
117362
T721
G
N
K
G
Y
A
Y
T
F
I
T
E
D
Q
A
Chimpanzee
Pan troglodytes
XP_517939
1173
133261
T863
G
N
K
G
Y
A
Y
T
F
I
T
E
D
Q
A
Rhesus Macaque
Macaca mulatta
XP_001109331
1031
117356
T721
G
N
K
G
Y
A
Y
T
F
I
T
E
D
Q
A
Dog
Lupus familis
XP_531911
1031
117344
T721
G
N
K
G
Y
A
Y
T
F
I
T
E
D
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q569Z5
1032
117430
T721
G
N
K
G
Y
A
Y
T
F
I
T
E
D
Q
A
Rat
Rattus norvegicus
Q62780
1032
117367
T721
G
N
K
G
Y
A
Y
T
F
I
T
E
D
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510706
974
110456
T664
G
N
K
G
H
A
F
T
F
I
T
E
D
Q
A
Chicken
Gallus gallus
Q5F485
944
103035
Q634
E
L
L
D
L
A
M
Q
N
P
W
F
R
K
S
Frog
Xenopus laevis
Q7ZY47
947
104061
G645
S
R
F
K
A
G
K
G
K
K
L
N
I
G
G
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
T689
G
N
K
G
Y
A
Y
T
F
I
T
E
G
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573020
1224
136263
T859
G
K
K
G
S
A
Y
T
F
I
T
P
E
Q
S
Honey Bee
Apis mellifera
XP_001122722
1018
114528
T705
G
N
K
G
Y
A
Y
T
F
I
T
S
E
Q
E
Nematode Worm
Caenorhab. elegans
NP_001033411
970
109887
T654
G
R
K
G
Y
A
Y
T
F
V
L
P
E
H
Q
Sea Urchin
Strong. purpuratus
XP_784902
869
99209
Q582
F
D
M
G
F
E
P
Q
V
M
K
I
V
E
N
Poplar Tree
Populus trichocarpa
XP_002301895
1112
128539
T821
G
R
K
G
C
A
I
T
F
I
S
E
D
D
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0U8
1166
133015
T878
G
R
K
G
C
A
V
T
F
I
S
E
D
D
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
V896
P
N
H
L
E
D
Y
V
H
R
A
G
R
T
G
Conservation
Percent
Protein Identity:
100
87.8
99.9
99.8
N.A.
98.8
98.6
N.A.
89.6
29.7
30.2
83
N.A.
49.6
63.8
47.8
54.5
Protein Similarity:
100
87.8
99.9
99.8
N.A.
99.5
99.3
N.A.
92.5
45.7
48.2
90.1
N.A.
62.9
75.9
65.9
65.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
6.6
0
93.3
N.A.
66.6
80
53.3
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
20
0
93.3
N.A.
80
86.6
66.6
33.3
Percent
Protein Identity:
43.9
N.A.
N.A.
43.3
N.A.
41.3
Protein Similarity:
60.1
N.A.
N.A.
58.5
N.A.
56.2
P-Site Identity:
66.6
N.A.
N.A.
66.6
N.A.
13.3
P-Site Similarity:
73.3
N.A.
N.A.
73.3
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
6
83
0
0
0
0
6
0
0
0
59
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
0
6
0
6
0
0
0
0
0
0
53
12
0
% D
% Glu:
6
0
0
0
6
6
0
0
0
0
0
59
18
6
6
% E
% Phe:
6
0
6
0
6
0
6
0
77
0
0
6
0
0
0
% F
% Gly:
77
0
0
83
0
6
0
6
0
0
0
6
6
6
12
% G
% His:
0
0
6
0
6
0
0
0
6
0
0
0
0
6
0
% H
% Ile:
0
0
0
0
0
0
6
0
0
71
0
6
6
0
0
% I
% Lys:
0
6
77
6
0
0
6
0
6
6
6
0
0
6
0
% K
% Leu:
0
6
6
6
6
0
0
0
0
0
12
0
0
0
0
% L
% Met:
0
0
6
0
0
0
6
0
0
6
0
0
0
0
0
% M
% Asn:
0
59
0
0
0
0
0
0
6
0
0
6
0
0
6
% N
% Pro:
6
0
0
0
0
0
6
0
0
6
0
12
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
12
0
0
0
0
0
59
6
% Q
% Arg:
0
24
0
0
0
0
0
0
0
6
0
0
12
0
0
% R
% Ser:
6
0
0
0
6
0
0
0
0
0
12
6
0
0
12
% S
% Thr:
0
0
0
0
0
0
0
77
0
0
59
0
0
6
0
% T
% Val:
0
0
0
0
0
0
6
6
6
6
0
0
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% W
% Tyr:
0
0
0
0
53
0
65
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _