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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX46
All Species:
42.73
Human Site:
Y294
Identified Species:
58.75
UniProt:
Q7L014
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L014
NP_055644.2
1031
117362
Y294
N
D
Q
D
A
M
E
Y
S
S
E
E
E
E
V
Chimpanzee
Pan troglodytes
XP_517939
1173
133261
Y436
N
D
Q
D
A
M
E
Y
S
S
E
E
E
E
V
Rhesus Macaque
Macaca mulatta
XP_001109331
1031
117356
Y294
N
D
Q
D
A
M
E
Y
S
S
E
E
E
E
V
Dog
Lupus familis
XP_531911
1031
117344
Y294
N
D
Q
D
A
M
E
Y
S
S
E
E
E
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q569Z5
1032
117430
Y294
N
D
Q
D
A
M
E
Y
S
S
E
E
E
E
V
Rat
Rattus norvegicus
Q62780
1032
117367
Y294
N
D
Q
D
A
M
E
Y
S
S
E
E
E
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510706
974
110456
Y237
N
D
Q
D
A
M
E
Y
S
S
E
E
E
E
V
Chicken
Gallus gallus
Q5F485
944
103035
S226
D
E
H
E
E
I
T
S
L
T
P
Q
Q
V
V
Frog
Xenopus laevis
Q7ZY47
947
104061
T225
H
E
A
I
T
S
Q
T
P
Q
Q
I
T
E
L
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
Y262
N
D
Q
D
A
M
E
Y
S
S
E
E
E
E
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573020
1224
136263
Y432
Q
N
M
D
S
L
E
Y
S
S
E
D
E
L
E
Honey Bee
Apis mellifera
XP_001122722
1018
114528
Y278
Q
N
Q
D
G
L
E
Y
S
S
E
E
E
G
E
Nematode Worm
Caenorhab. elegans
NP_001033411
970
109887
M227
V
L
E
N
E
D
N
M
D
M
V
I
D
D
F
Sea Urchin
Strong. purpuratus
XP_784902
869
99209
M193
Q
R
R
L
E
E
E
M
Q
K
R
R
E
R
I
Poplar Tree
Populus trichocarpa
XP_002301895
1112
128539
L392
S
D
S
D
Y
G
D
L
E
N
G
E
D
P
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0U8
1166
133015
G351
E
T
K
P
E
N
D
G
D
A
K
M
V
D
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
D482
E
A
Y
F
S
D
D
D
Y
G
Y
E
A
D
G
Conservation
Percent
Protein Identity:
100
87.8
99.9
99.8
N.A.
98.8
98.6
N.A.
89.6
29.7
30.2
83
N.A.
49.6
63.8
47.8
54.5
Protein Similarity:
100
87.8
99.9
99.8
N.A.
99.5
99.3
N.A.
92.5
45.7
48.2
90.1
N.A.
62.9
75.9
65.9
65.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
6.6
6.6
100
N.A.
46.6
60
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
53.3
40
100
N.A.
73.3
73.3
26.6
26.6
Percent
Protein Identity:
43.9
N.A.
N.A.
43.3
N.A.
41.3
Protein Similarity:
60.1
N.A.
N.A.
58.5
N.A.
56.2
P-Site Identity:
20
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
53.3
N.A.
N.A.
40
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
6
0
48
0
0
0
0
6
0
0
6
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
53
0
65
0
12
18
6
12
0
0
6
12
18
0
% D
% Glu:
12
12
6
6
24
6
65
0
6
0
59
65
65
53
12
% E
% Phe:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
6
% F
% Gly:
0
0
0
0
6
6
0
6
0
6
6
0
0
6
6
% G
% His:
6
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
6
0
6
0
0
0
0
0
12
0
0
6
% I
% Lys:
0
0
6
0
0
0
0
0
0
6
6
0
0
0
0
% K
% Leu:
0
6
0
6
0
12
0
6
6
0
0
0
0
6
18
% L
% Met:
0
0
6
0
0
48
0
12
0
6
0
6
0
0
0
% M
% Asn:
48
12
0
6
0
6
6
0
0
6
0
0
0
0
0
% N
% Pro:
0
0
0
6
0
0
0
0
6
0
6
0
0
6
0
% P
% Gln:
18
0
53
0
0
0
6
0
6
6
6
6
6
0
0
% Q
% Arg:
0
6
6
0
0
0
0
0
0
0
6
6
0
6
0
% R
% Ser:
6
0
6
0
12
6
0
6
59
59
0
0
0
0
0
% S
% Thr:
0
6
0
0
6
0
6
6
0
6
0
0
6
0
0
% T
% Val:
6
0
0
0
0
0
0
0
0
0
6
0
6
6
53
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
6
0
6
0
0
59
6
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _