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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX46
All Species:
44.85
Human Site:
Y392
Identified Species:
61.67
UniProt:
Q7L014
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L014
NP_055644.2
1031
117362
Y392
N
S
L
K
K
H
G
Y
E
K
P
T
P
I
Q
Chimpanzee
Pan troglodytes
XP_517939
1173
133261
Y534
N
S
L
K
K
H
G
Y
E
K
P
T
P
I
Q
Rhesus Macaque
Macaca mulatta
XP_001109331
1031
117356
Y392
N
S
L
K
K
H
G
Y
E
K
P
T
P
I
Q
Dog
Lupus familis
XP_531911
1031
117344
Y392
N
S
L
K
K
H
G
Y
E
K
P
T
P
I
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q569Z5
1032
117430
Y392
N
S
L
K
K
H
G
Y
E
K
P
T
P
I
Q
Rat
Rattus norvegicus
Q62780
1032
117367
Y392
N
S
L
K
K
H
G
Y
E
K
P
T
P
I
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510706
974
110456
Y335
N
S
L
R
K
H
G
Y
E
K
P
T
P
I
Q
Chicken
Gallus gallus
Q5F485
944
103035
G326
K
E
L
E
P
G
D
G
P
I
A
V
I
V
C
Frog
Xenopus laevis
Q7ZY47
947
104061
G323
K
E
L
Q
P
A
D
G
P
I
A
V
I
V
C
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
Y360
N
A
L
K
K
H
N
Y
E
K
P
T
P
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573020
1224
136263
F530
E
V
L
R
R
L
G
F
E
K
P
T
P
I
Q
Honey Bee
Apis mellifera
XP_001122722
1018
114528
Y376
E
V
L
K
K
L
G
Y
E
K
P
T
P
I
Q
Nematode Worm
Caenorhab. elegans
NP_001033411
970
109887
Y324
N
V
L
K
K
F
E
Y
S
K
P
T
S
I
Q
Sea Urchin
Strong. purpuratus
XP_784902
869
99209
P290
S
K
D
K
K
G
P
P
A
V
E
K
A
T
G
Poplar Tree
Populus trichocarpa
XP_002301895
1112
128539
Y492
E
T
I
K
K
L
N
Y
E
K
P
M
T
I
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0U8
1166
133015
Y549
D
T
M
K
K
L
N
Y
E
K
P
M
P
I
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
F581
D
T
I
E
S
L
G
F
E
K
P
T
P
I
Q
Conservation
Percent
Protein Identity:
100
87.8
99.9
99.8
N.A.
98.8
98.6
N.A.
89.6
29.7
30.2
83
N.A.
49.6
63.8
47.8
54.5
Protein Similarity:
100
87.8
99.9
99.8
N.A.
99.5
99.3
N.A.
92.5
45.7
48.2
90.1
N.A.
62.9
75.9
65.9
65.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
6.6
6.6
86.6
N.A.
60
80
66.6
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
20
20
93.3
N.A.
80
80
66.6
20
Percent
Protein Identity:
43.9
N.A.
N.A.
43.3
N.A.
41.3
Protein Similarity:
60.1
N.A.
N.A.
58.5
N.A.
56.2
P-Site Identity:
53.3
N.A.
N.A.
60
N.A.
53.3
P-Site Similarity:
66.6
N.A.
N.A.
80
N.A.
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
0
0
6
0
0
6
0
12
0
6
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% C
% Asp:
12
0
6
0
0
0
12
0
0
0
0
0
0
0
0
% D
% Glu:
18
12
0
12
0
0
6
0
77
0
6
0
0
0
0
% E
% Phe:
0
0
0
0
0
6
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
59
12
0
0
0
0
0
0
6
% G
% His:
0
0
0
0
0
48
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
0
0
0
0
12
0
0
12
83
0
% I
% Lys:
12
6
0
71
77
0
0
0
0
83
0
6
0
0
0
% K
% Leu:
0
0
77
0
0
30
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
6
0
0
0
0
0
0
0
0
12
0
0
0
% M
% Asn:
53
0
0
0
0
0
18
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
12
0
6
6
12
0
83
0
71
0
0
% P
% Gln:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
83
% Q
% Arg:
0
0
0
12
6
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
6
42
0
0
6
0
0
0
6
0
0
0
6
0
0
% S
% Thr:
0
18
0
0
0
0
0
0
0
0
0
71
6
6
0
% T
% Val:
0
18
0
0
0
0
0
0
0
6
0
12
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
71
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _