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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX46
All Species:
54.24
Human Site:
Y525
Identified Species:
74.58
UniProt:
Q7L014
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L014
NP_055644.2
1031
117362
Y525
T
N
L
R
R
V
T
Y
V
V
L
D
E
A
D
Chimpanzee
Pan troglodytes
XP_517939
1173
133261
Y667
T
N
L
R
R
V
T
Y
V
V
L
D
E
A
D
Rhesus Macaque
Macaca mulatta
XP_001109331
1031
117356
Y525
T
N
L
R
R
V
T
Y
V
V
L
D
E
A
D
Dog
Lupus familis
XP_531911
1031
117344
Y525
T
N
L
R
R
V
T
Y
V
V
L
D
E
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q569Z5
1032
117430
Y525
T
N
L
R
R
V
T
Y
V
V
L
D
E
A
D
Rat
Rattus norvegicus
Q62780
1032
117367
Y525
T
N
L
R
R
V
T
Y
V
V
L
D
E
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510706
974
110456
Y468
T
N
L
R
R
V
T
Y
V
V
L
D
E
A
D
Chicken
Gallus gallus
Q5F485
944
103035
Q461
I
D
P
I
R
V
V
Q
G
D
I
G
E
A
N
Frog
Xenopus laevis
Q7ZY47
947
104061
Q458
V
D
P
I
R
V
V
Q
G
D
I
G
E
A
N
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
Y493
T
N
L
R
R
V
T
Y
V
V
I
D
E
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573020
1224
136263
Y663
T
N
L
R
R
V
T
Y
V
V
L
D
E
A
D
Honey Bee
Apis mellifera
XP_001122722
1018
114528
Y509
T
N
L
R
R
V
T
Y
V
V
L
D
E
A
D
Nematode Worm
Caenorhab. elegans
NP_001033411
970
109887
Y457
T
N
L
R
R
V
T
Y
L
V
L
D
E
A
D
Sea Urchin
Strong. purpuratus
XP_784902
869
99209
M421
W
V
Q
C
G
V
S
M
R
V
L
T
I
L
K
Poplar Tree
Populus trichocarpa
XP_002301895
1112
128539
Y625
T
N
L
R
R
V
T
Y
L
V
M
D
E
A
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8H0U8
1166
133015
F682
T
N
L
R
R
V
T
F
L
V
M
D
E
A
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
Y714
T
N
L
K
R
A
T
Y
L
V
L
D
E
A
D
Conservation
Percent
Protein Identity:
100
87.8
99.9
99.8
N.A.
98.8
98.6
N.A.
89.6
29.7
30.2
83
N.A.
49.6
63.8
47.8
54.5
Protein Similarity:
100
87.8
99.9
99.8
N.A.
99.5
99.3
N.A.
92.5
45.7
48.2
90.1
N.A.
62.9
75.9
65.9
65.8
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
26.6
26.6
93.3
N.A.
100
100
93.3
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
46.6
46.6
100
N.A.
100
100
100
26.6
Percent
Protein Identity:
43.9
N.A.
N.A.
43.3
N.A.
41.3
Protein Similarity:
60.1
N.A.
N.A.
58.5
N.A.
56.2
P-Site Identity:
86.6
N.A.
N.A.
80
N.A.
80
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
93.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
6
0
0
0
0
0
0
0
95
0
% A
% Cys:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
0
0
0
12
0
83
0
0
83
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
95
0
0
% E
% Phe:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
6
0
0
0
12
0
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
0
0
12
0
0
0
0
0
0
18
0
6
0
0
% I
% Lys:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
6
% K
% Leu:
0
0
83
0
0
0
0
0
24
0
71
0
0
6
0
% L
% Met:
0
0
0
0
0
0
0
6
0
0
12
0
0
0
0
% M
% Asn:
0
83
0
0
0
0
0
0
0
0
0
0
0
0
12
% N
% Pro:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
6
0
0
0
0
12
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
77
95
0
0
0
6
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% S
% Thr:
83
0
0
0
0
0
83
0
0
0
0
6
0
0
0
% T
% Val:
6
6
0
0
0
95
12
0
59
89
0
0
0
0
0
% V
% Trp:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _